721948-65-8

Usage

Uses

Used in Plant Hormone Research:
(+)-cis,trans-Abscisic Acid-d6 is used as a research compound for studying the effects and mechanisms of the abscission-accelerating plant hormone. Its isotopic nature allows for easier tracking and analysis in various biological systems.
Used in Agricultural Applications:
In the agricultural industry, (+)-cis,trans-Abscisic Acid-d6 is used as a growth regulator to control plant development, particularly in the process of abscission, which is the shedding of leaves, flowers, or fruits from a plant.
Used in Pharmaceutical Applications:
(+)-cis,trans-Abscisic Acid-d6 is used as a potential therapeutic agent in the development of drugs targeting plant hormone-related conditions, such as stress responses in plants, which may have implications for human health and disease.
Used in Environmental Applications:
In environmental science, (+)-cis,trans-Abscisic Acid-d6 can be used to study the effects of plant hormones on ecosystems and their potential role in climate change adaptation and mitigation strategies.
Used in Analytical Chemistry:
As a stable isotopic analog, (+)-cis,trans-Abscisic Acid-d6 is used in analytical chemistry for the development of sensitive and accurate methods for the detection and quantification of plant hormones in various samples, including plant tissues, soil, and water.

Upstream product

• 2228-72-0 Abscisic acid 

Relevant academic research and scientific papers

Fragmentation of methyl abscisate and pentafluorobenzyl abscisate in methane electron capture negative ionization tandem mass spectrometry

The methyl and pentafluorobenzyl esters of the plant hormone abscisic acid were subjected to methane chemical ionization tandem mass spectrometry (MS/MS). The spectra obtained allow the unambiguous identification of abscisic acid in a few milligrams of plant material. In full-scan mode pentafluorobenzyl (PFB) abscisate (ABA) gave three significant ions at m/z 263 ([M-PFB]-), m/z 219 ([M-PFB-CO2]-) and m/z 153 ([M-PFB-side chain]-). Each of these was subjected to MS/MS and structures were assigned to the product ions using the labelled analogues, PFB[1'-18O]ABA, PFB[4'-18O]ABA, PFB[side-chain-2H4]ABA and PFB[ring-2H6]ABA. Similarly, in full-scan mode, methyl abscisate gave three significant ions at m/z 278 (M-), m/z 260 ([M-H2O]-) and m/z 245 ([M-H-CH3OH]-) and in MS/MS the use of the methyl esters of the above labelled analogues, and [2H]methyl abscisate, allowed structures to be assigned to the product ions. Using these results it will be possible to dissect abscisic acid so that most labelled atoms from 13C-labelled substrates will be able to be uniquely identified from a few nanograms of 13C-labelled abscisic acid. If sufficient incorporation of 13C-labelled substrates can be obtained it should be possible to investigate the pathway(s) of abscisic acid biosynthesis using less than 1 g of plant material.

Deuterium-labeled phaseic acid and dihydrophaseic acids for internal standards.

The concentration of abscisic acid in plants is regulated not only by biosynthesis, but also by metabolism. Abscisic acid is metabolized to phaseic acid via 8'-hydroxyabscisic acid, and phaseic acid is then converted to dihydrophaseic acid and its epimer. A quantitative analysis of these metabolites is important as well as that of abscisic acid to understand changes in the concentration of abscisic acid in plants. However, no internal standards of the metabolites suitable for quantitative analysis have been reported. We prepared 7'-deuterium-labeled phaseic acid with a deuterium content of 86%, using the equilibrium reaction between phaseic acid and 8'-hydroxyabscisic acid. 7'-Deuterium-labeled dihydrophaseic acids were obtained by reducing 7'-deuterium-labeled phaseic acid. The levels of the metabolites in plant organs were determined by using the deuterated metabolites as internal standards.