72198-83-5

Basic information

• Product Name: 3-METHYL-4-NITROBENZHYDRAZIDE
• Synonyms: ART-CHEM-BB B014939;3-METHYL-4-NITROBENZENE-1-CARBOHYDRAZIDE;3-METHYL-4-NITROBENZHYDRAZIDE;AKOS B014939;680370_ALDRICH;Maybridge1_006277;SR-01000631842-1;STK082873
• CAS NO: 72198-83-5
• Molecular Formula: C₈H₉N₃O₃
• Molecular Weight: 195.18
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;Carbonyl Compounds;Hydrazides;Organic Building Blocks
• Mol File: 72198-83-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 147-149°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.345g/cm³
• Refractive Index: 1.607
• CAS DataBase Reference: 3-METHYL-4-NITROBENZHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-4-NITROBENZHYDRAZIDE(72198-83-5)
• EPA Substance Registry System: 3-METHYL-4-NITROBENZHYDRAZIDE(72198-83-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39-36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 72198-83-5(Hazardous Substances Data)

Usage

General Description

3-Methyl-4-nitrobenzhydrazide is a chemical compound with the molecular formula C8H8N4O2. It is a yellow crystalline solid that is often used as a reagent in various chemical reactions. 3-METHYL-4-NITROBENZHYDRAZIDE is primarily utilized in the synthesis of pharmaceuticals, dyes, and agrochemicals. It is also used as a stabilizer for explosives and as a reagent for the detection and determination of metals in analytical chemistry. 3-Methyl-4-nitrobenzhydrazide is considered to be potentially harmful if ingested, inhaled, or if it comes into contact with the skin, and it may cause irritation to the respiratory system, skin, and eyes. Therefore, it should be handled and stored with proper care and precaution.

InChI:InChI=1/C8H9N3O3/c1-5-4-6(8(12)10-9)2-3-7(5)11(13)14/h2-4H,9H2,1H3,(H,10,12)

Upstream product

• 24078-21-5 methyl 3-methyl-4-nitrobenzoate 

Downstream Products

• 126632-47-1 diethyl N-(3-methyl-4-nitrobenzoyl)-L-glutamate 
• 103503-71-5 N-<4-(N'-(2,4-diaminopteridin-6-ylmethyl)amino)-3-methylbenzoyl>-L-glutamic acid 
• 287942-21-6 N'-(2,2-dimethylpropanoyl)-3-methyl-4-nitrobenzhydrazide 
• 1201594-84-4 2-cyclopentyl-5-(3-methyl-4-nitrophenyl)-1,3,4-thiadiazole 
• 1201594-71-9 2-cyclopentyl-5-(3-methyl-4-nitrophenyl)-1,3,4-oxadiazole 
• 1030549-98-4 2-(3-methoxyphenyl)-5-(3-methyl-4-nitrophenyl)-1,3,4-oxadiazole 
• 1201594-89-9 tert-butyl-4-[5-(3-methyl-4-nitrophenyl)-1,3,4-thiadiazol-2-yl]-piperidine-1-carboxylate 
• 1391436-64-8 sodium 2-[(3-methyl-4-nitro-benzoyl)-hydrazono]-propionate 
• 1430092-80-0 C₁₅H₁₁N₃O₄S 

Relevant articles and documents

Aromatic acyl hydrazone derivative and application thereof as NA inhibitor

The invention relates to an aromatic acyl hydrazone derivative as shown in a structural formula I, pharmaceutically acceptable salt and a pharmaceutical composition thereof, and application of the aromatic acyl hydrazone derivative and the pharmaceutically acceptable salt and the pharmaceutical composition in preparation of an influenza virus neuraminidase inhibitor, wherein R is one of trifluoromethyl, nitryl, 3-methyl-4-nitryl, 3-hydroxyl-4-nitryl, 3-nitryl-4-hydroxyl, hydroxyl, dihydroxyl, dinitryl, 3-methoxy-4-hydroxyl or trihydroxyl; Y is selected from hydroxyl, dihydroxyl, 2-hydroxyl-3-methoxy, 2-hydroxyl-4-methoxy,2-hydroxyl-5-methoxy,2-hydroxyl-6-methoxy,3-hydroxyl-2-methoxy,3-hydroxyl-4-methoxy,3-hydroxyl-5-methoxy,3-hydroxyl-6-methoxy,4-hydroxyl-2-methoxy,4-hydroxyl-3-methoxy,4-hydroxyl-3,5-dimethoxy, trihydroxyl, 4-hydroxyl-3-ethoxy, or 4-hydroxyl-3,5-dimethoxy; w is selected from CH or N; and z is selected from CH or N.