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2-Nitrotyrosine is a chemical compound formed when nitric oxide reacts with the amino acid tyrosine, which is a crucial component of proteins. This reaction occurs during inflammation and oxidative stress, leading to the formation of nitrotyrosine residues in proteins. 2-Nitrotyrosine is considered a biomarker for oxidative stress and nitrosative stress, as it can be used to assess the extent of protein nitration in various pathological conditions, such as neurodegenerative diseases, cardiovascular diseases, and cancer. The presence of 2-nitrotyrosine in biological samples can be detected using mass spectrometry, immunoassays, and other analytical techniques, providing valuable insights into the underlying mechanisms of oxidative and nitrosative stress in these diseases.

7220-53-3

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7220-53-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7220-53-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,2 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7220-53:
(6*7)+(5*2)+(4*2)+(3*0)+(2*5)+(1*3)=73
73 % 10 = 3
So 7220-53-3 is a valid CAS Registry Number.

7220-53-3Downstream Products

7220-53-3Relevant academic research and scientific papers

Immunomodulatory peptides

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, (2014/12/12)

The invention relates to peptides derivatized with a hydrophilic polymer which, in some embodiments, bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used in some embodiments, for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates, in further embodiments, to methods of using and methods of making the peptides of the invention.

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