72228-43-4 Usage
Derivative of indole
2-(1,2-dimethyl-1H-indol-3-yl)propanoic acid is derived from the compound indole, which is a structural feature found in many biologically important molecules.
Pharmaceutical industry use
2-(1,2-dimethyl-1H-indol-3-yl)propanoic acid is commonly used in the pharmaceutical industry, which suggests that it may have potential therapeutic applications.
Inhibition of enzymes and receptors
2-(1,2-dimethyl-1H-indol-3-yl)propanoic acid has the ability to inhibit various enzymes and receptors in the body, which may be useful in the treatment of certain diseases.
Anti-inflammatory and neuroprotective properties
2-(1,2-dimethyl-1H-indol-3-yl)propanoic acid has been studied for its potential anti-inflammatory and neuroprotective properties, which may be useful in the treatment of conditions such as arthritis or neurodegenerative diseases.
Potential use in the treatment of cancer and neurological disorders
2-(1,2-dimethyl-1H-indol-3-yl)propanoic acid is being researched for its potential use in the treatment of various diseases, including cancer and neurological disorders. This suggests that it may have therapeutic potential in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 72228-43-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,2,2 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 72228-43:
(7*7)+(6*2)+(5*2)+(4*2)+(3*8)+(2*4)+(1*3)=114
114 % 10 = 4
So 72228-43-4 is a valid CAS Registry Number.
72228-43-4Relevant academic research and scientific papers
α-Lithio-3-indolylacetate Synthons: Generation and Synthetic Utilization
Adam, Waldemar,Takayama, Kiyoshige
, p. 447 - 452 (2007/10/02)
3-Indolyl-, (N-methyl-3-indolyl)-, and (N-methyl-2-methyl-3-indolyl)acetic acids are quantitatively α-lithiated directly with n-BuLi, while methyl (N-methyl-3-indolyl)acetate is quantitatively α-lithiated with lithium diisopropylamide (LDA) at -78 deg C in THF.These useful synthons react readily with electrophiles such as alkyl halides, chlorosilanes, and ketones to afford the respective α-alkyl derivatives 1, ketene silyl acetals 2, and β-hydroxy acids 3.Photosensitized oxygenation of the ketene silyl acetals 2 affords 1,2-diox-4-ene products through (2 + 4) cycloaddition with singlet oxygen.
