72236-82-9Relevant academic research and scientific papers
Chemistry of 6H-pyridocarbazoles. Part 9. An Efficient Route to 3-indoles and the Synthesis of Some New Ellipticines
Sainsbury, Malcolm,Weerasinghe, Deepthi,Dolman, David
, p. 587 - 590 (2007/10/02)
A new and efficient route to 3-indoles has been developed which requires the Fisher indolisation of 3-(3-pyridyl)butanal with arylhydrazines.The ethylpyridylindoles can be converted into 6H-pyridocarbazoles by a known procedure, leading to the first synthesis of 7-chloro-, 7-fluoro-, 7-methyl-, 8-methoxy-, and 8-hydroxy-ellipticines.The last-named compound is identical with a minor metabolite of ellipticine in Aspergillus alliaceus.
THE SYNTHESIS OF 8-HYDROXY- AND 8-METHOXY-ELLIPTICINES
Dolman, David,Sainsbury, Malcolm
, p. 2119 - 2120 (2007/10/02)
The first synthesis of 8-hydroxyellipticine is described and its identity with an ellipticine metabolite from Aspergillus alliaceus confirmed.
