72238-87-0Relevant academic research and scientific papers
Activation of 1,1-difluoro-1-alkenes with a transition-metal complex: Palladium(II)-catalyzed friedel - crafts-type cyclization of 4,4-(difluorohomoallyl)arenes
Yokota, Misaki,Fujita, Daishi,Ichikawa, Junji
, p. 4639 - 4642 (2007)
(Chemical Equation Presented) Cationic palladium(II) ([Pd(MeCN) 4](BF4)2) provides the first transition-metal-catalyzed method for electrophilic activation of electron-deficient 1,1-difluoro-1-alkenes, which allows their Friedel-Crafts-type cyclization with an intramolecular aryl group via a Wacker-type process. By using BF3·OEt2, the cyclization was effected by a catalytic amount of the palladium without its reoxidation.
