72247-82-6

Usage

Uses

Used in Pharmaceutical Industry:
8-Prenyl-rac-pinocembrin is used as a pharmaceutical agent for its potential therapeutic effects. Its unique chemical structure allows it to interact with various biological targets, making it a promising candidate for the development of new drugs.
Used in Nutraceutical Industry:
8-Prenyl-rac-pinocembrin can be used as a nutraceutical ingredient due to its potential health benefits. Its antioxidant and anti-inflammatory properties may contribute to the prevention and treatment of various diseases and conditions.
Used in Cosmetic Industry:
8-Prenyl-rac-pinocembrin can be used in cosmetic products for its potential skin health benefits. Its antioxidant and anti-inflammatory properties may help protect the skin from environmental damage and promote a healthy complexion.
Used in Food Industry:
8-Prenyl-rac-pinocembrin can be used as a natural food additive for its potential health benefits. Its antioxidant properties may help preserve the freshness and quality of food products while providing additional health benefits to consumers.

Upstream product

• 1075171-40-2 5,7-dimethoxymethoxy-8-(3,3-dimethylallyl)-flavanone 
• 394249-09-3 2,4,6-tri(methoxymethoxy)-3-C-prenylacetophenone 
• 36804-11-2 2,4,6-tri-MOM phloracetophenone 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 72247-78-0 (E)-3-phenyl-1-(2,4,6-trihydroxy-3-(3-methylbut-2-enyl)phenyl)prop-2-en-1-one 
• 480-39-7 pinocembrin 
• 780724-90-5 dimethylallyl diphosphate 
• 870-63-3 prenyl bromide 

Downstream Products

• 75291-75-7 5-hydroxy-7-methoxy-3-C-prenylflavone 

Relevant academic research and scientific papers

Identification of SVM-based classification model, synthesis and evaluation of prenylated flavonoids as vasorelaxant agents

Support vector machine (SVM) was applied to predict vasorelaxation effect of different structural molecules. A good classification model had been established, and the accuracy in prediction for the training, test, and overall datasets was 93.0%, 82.6%, an

Synthesis of 5,7-dihydroxy-8-C-prenylflavanone

5,7-Dihydroxy-8-C-prenylflavanone (VII, glabranin) Mitscher et al 1983) isolated from the roots and stems of Glycyrriza lepidota has been synthesized by following unambigous route. All the new products have been characterized on the basis of spectral data

Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures

Dimethylallyl diphosphate: naringenin 8-dimethylallyltransferase (EC 2.5.1) was characterized. The enzyme was enantiospecific for (-)-(2S)-naringenin and utilized 3,3-dimethylallyl diphosphate as sole prenyl donor. It required Mg2+ (optimum concentration, 10 mM), and has an optimum pH of 9-10. The apparent K(m) values for 3,3-dimethylallyl diphosphate and naringenin were 120 and 36 μM, respectively. The microsomal fraction prenylated several other flavanones at the C-8 position less effectively as compared with naringenin. Interestingly, when 2'-hydroxynaringenin was used as a prenyl acceptor, the 8-lavandulyl (sophoraflavanone G) and the 6-dimethylallyl derivatives were formed, together with the 8-dimethylallyl derivative, leachianone G. These results suggest that the 2'-hydroxy group of naringenin plays an important role for the formation of a lavandulyl group. (C) 2000 Elsevier Science Ltd.

Variations in the chemical shift of the 5-hydroxyl proton of 7-o-prenylated flavanones

In 1H nmr examination of 6- or 8-prenylated flavanone 7-methyl and 7-prenyl ethers, the signals of hydrogen-bonded hydroxyl proton appeared in relatively narrow region. Relatively large solvent effect was observed on the signal of 6-prenylflavanone 7-methyl and 7-prenyl ethers.