722549-18-0

Usage

General Description

2-Propenal,3-[2-(trifluoromethyl)phenyl]-(9CI), also known as 2-(Trifluoromethyl)styryl aldehyde, is a chemical compound with the molecular formula C10H7F3O. It is a yellow liquid with a strong, pungent odor and is primarily used as a building block in the synthesis of other organic compounds. This chemical is commonly used in the production of pharmaceuticals, dyes, and agrochemicals. It is also used as a reagent in organic chemical reactions, particularly in the field of synthetic chemistry. Additionally, it has applications in the field of materials science, where it is used in the synthesis of polymers and other advanced materials. Overall, 2-Propenal,3-[2-(trifluoromethyl)phenyl]-(9CI) is an important industrial chemical with a wide range of applications in various fields.

Upstream product

• 447-61-0 2-Trifluoromethylbenzaldehyde 
• 75-07-0 acetaldehyde 
• 127896-07-5 α,α-bis(trimethylsilyl)-tert-butylacetaldehyde imine 

Downstream Products

• 123486-68-0 2-Methyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 1223035-17-3 (S)-3-(1-methyl-1H-pyrrol-2-yl)-3-(2-(trifluoromethyl)phenyl)propan-1-ol 
• 1617533-05-7 1-phenyl-3-(trifluoromethyl)-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridazine 
• 1449691-50-2 C₁₇H₁₅F₃O₃ 
• 1354046-12-0 (S)-3-(1-methyl-1H-indol-3-yl)-3-(2-(trifluoromethyl)phenyl)propan-1-ol 
• 1061335-54-3 (2R,4S)-5-oxo-4-(2-(trifluoromethyl)phenyl)-2,3,4,5,6,7-hexahydrocyclopenta[b]pyran-2-yl acetate 
• 123486-70-4 diethyl (3aα,4α,7aα)-3a,4,7,7a-tetrahydro-6-methyl-4-<2-(trifluoromethyl)phenyl>isoxazolo<5,4-b>pyridine-3,5-dicarboxylate 

Relevant academic research and scientific papers

Method for preparing olefine aldehyde by catalyzing terminal alkyne or terminal conjugated eneyne and diphosphine ligand used in method

The invention discloses a method for preparing olefine aldehyde by catalyzing terminal alkyne or terminal conjugated eneyne and a diphosphine ligand used in the method. According to the invention, indole-substituted phosphoramidite diphosphine ligand which is stable in air and insensitive to light is synthesized by utilizing a continuous one-pot method, and the indole-substituted phosphoramidite diphosphine ligand and a rhodium catalyst are used for jointly catalyzing to successfully achieve a hydroformylation reaction of aromatic terminal alkyne and terminal conjugated eneyne under the condition of synthesis gas for the first time, so that an olefine aldehyde structure compound can be rapidly and massively prepared, and particularly, a polyolefine aldehyde structure compound which is more difficult to synthesize in the prior art can be easily prepared and synthesized, and a novel method is provided for synthesis and modification of drug molecules, intermediates and chemical products.

METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY

The present invention provides compositions and formulations of compounds having formula (I) and pharmaceutically acceptable derivatives thereof, wherein p, R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of injuries, conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role. In addition, methods are provided for treating such diseases or diseases starting at a time after the onset of the injury, condition or disease.