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5-Benzyloxylmethyl-3',5'-di-O-toluoyl-2'-deoxyuridine is a complex organic compound that belongs to the class of nucleoside derivatives. It is characterized by a unique structure, where a benzyloxylmethyl group is attached to the 5-position of the uracil base, and two toluoyl groups are esterified to the 3' and 5' positions of the deoxyribose sugar moiety. 5-benzyloxymethyl-3',5'-di-O-toluoyl-2'-deoxyuridine is of interest in medicinal chemistry and drug development due to its potential applications as an antiviral agent or as a building block in the synthesis of more complex nucleoside analogs. The toluoyl groups provide protection to the sugar, which is crucial for certain chemical reactions, while the benzyloxylmethyl group may influence the compound's pharmacokinetic properties, such as solubility and membrane permeability. The specific arrangement of these functional groups can affect the compound's interaction with enzymes and receptors, making it a valuable candidate for further investigation in the development of new therapeutics.

7226-75-7

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7226-75-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7226-75-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,2 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7226-75:
(6*7)+(5*2)+(4*2)+(3*6)+(2*7)+(1*5)=97
97 % 10 = 7
So 7226-75-7 is a valid CAS Registry Number.

7226-75-7Relevant academic research and scientific papers

Preparation of oligodeoxynucleotides containing 5-(N-methylpiperazinyl) and 5-benzyloxymethyl uracils

Megied, Ahmed E.-S. Abdel,Ali, Omar M.,Kofoed, Thomas,Pedersen, Erik B.

, p. 1 - 10 (2007/10/03)

Deprotected compounds 1 and 9 were allowed to react with 4,4'-dimethoxytrityl chloride in pyridine to give 5'-O-DMT nucleosides 2 and 10. The 3'-phosphoramidites 4 and 11 were incorporated into oligodeoxynucleosides (ODNs). The hybridization properties of the modified ODNs with their complementary DNA strands were studied. Interesting results were obtained when 11 was inserted as a bulged nucleoside into TWAs, duplexes, and triplexes.

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