72305-24-9Relevant academic research and scientific papers
HETEROCYCLIC COMPOUNDS AS CCR2B ANTAGONISTS
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Page/Page column 187-188, (2008/06/13)
Compounds of formula (I) Q-L-W-C(=X)-Z-P wherein Q is an amine of the formula-N (R1)(R2); L is an alkyl or heterocyclyl-alkyl linker; W is a 6-or 7-membered aliphatic ring comprising ring atoms Y1 and Y2 which are linked to groups L and C(X) respectively and Y1 and Y2 are independently selected from N and C; X is O, N, N-CN or S; Z is NR 3; P is an optionally substituted monocyclic or bicyclic aryl or heteroaryl group; and pharmaceutically acceptable salts or solvates thereof, are useful in the treatment of C-C chemokine mediated conditions.
Synthesis of 5-membered ring-type compounds as potential cholecystokinin receptor ligands
Pentassuglia,Luca Araldi,Donati,Feriani,Oliosi,Pasquarello,Ursini
, p. 573 - 581 (2007/10/03)
Imidazolidine-2,4-diones and 1,5-diphenyl tetrainic acid derivatives were selected in order to evaluate some 5-membered heterocyclic ring compounds as potential templates for the synthesis of CCK receptor ligands. All the compounds were evaluated in vitro towards both CCK-B and CCK-A receptors.
