72315-45-8 Usage
Uses
Used in Pharmaceutical Industry:
1,3-Dibromo-imidazo[1,5-a]pyridine is used as a key intermediate in the synthesis of antiviral and antifungal medications. Its unique structure allows for the development of new drugs with improved efficacy and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical field, 1,3-dibromo-imidazo[1,5-a]pyridine serves as a building block for the creation of new compounds with pesticidal properties, helping to combat various plant diseases and pests.
Used in Research and Development:
Due to its distinctive structure and reactivity, 1,3-dibromo-imidazo[1,5-a]pyridine is also utilized in the research and development of novel organic compounds and materials, contributing to advancements in various scientific fields.
Safety Precautions:
As with any chemical, it is crucial to follow proper handling and safety procedures when working with 1,3-dibromo-imidazo[1,5-a]pyridine to ensure the well-being of researchers and workers in the laboratory or industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 72315-45-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,3,1 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 72315-45:
(7*7)+(6*2)+(5*3)+(4*1)+(3*5)+(2*4)+(1*5)=108
108 % 10 = 8
So 72315-45-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H4Br2N2/c8-6-5-3-1-2-4-11(5)7(9)10-6/h1-4H
72315-45-8Relevant academic research and scientific papers
Palladium-catalyzed C-H bond direct alkynylation of 5-membered heteroarenes: A well-defined synthetic route to azole derivatives containing two different alkynyl groups
Shibahara, Fumitoshi,Dohke, Yoshimasa,Murai, Toshiaki
experimental part, p. 5381 - 5388 (2012/08/27)
A widely applicable oxidative coupling of 5-membered heteroarenes and terminal alkynes that uses a combination of palladium and silver salts was developed. Under suitable conditions, imidazole and benzimidazole, which are sluggish under similar previously reported oxidative coupling conditions, as well as imidazo[1,5-a]pyridines, oxazole, benzoxazole, thiazole, and benzothiazole could be alkynylated. In addition, the bromine atom on the substrates was intact under the reaction conditions, and conventional Sonogashira coupling did not occur at all. With these reactivities in hand, a well-defined synthetic route to imidazo[1,5-a]pyridines and thiazole containing two different alkynyl groups was achieved in a simple manner. In addition, linear correlations were observed between the fluorescence wavelength and the Hammett substituent constants of aryl groups, not only on the C1- but also on the C3-alkynyl group of the obtained 1,3-bis(arylethynyl)imidazo [1,5-a]pyridines.
