723281-55-8

Basic information

• Product Name: N-MORPHOLINYL 3-BORONOBENZAMIDE
• Synonyms: N-MORPHOLINYL 3-BORONOBENZAMIDE;3-(4-MORPHOLINYLCARBONYL)PHENYLBORONIC ACID;3-(MORPHOLINE-4-CARBONYL)BENZENEBORONIC ACID;3-(MORPHOLINE-4-CARBONYL)PHENYLBORONIC ACID;3-(Morpholine-4-carbonyl)benzeneboronic acid 96%;(3-boronophenyl)(morpholin-4-yl)methanone;4-(3-Boronobenzoyl)morpholine;3-(4-Morpholinylcarbonyl)benzeneboronic acid, 98%
• CAS NO: 723281-55-8
• Molecular Formula: C₁₁H₁₄BNO₄
• Molecular Weight: 235.04
• Product Categories: blocks;BoronicAcids;Boronate Ester;Boronic Acid;Potassium Trifluoroborate;Boric Acid| Boric Acid Ester| Potassium Trifluoroborate
• Mol File: 723281-55-8.mol

Chemical Properties

• Melting Point: 124-130°C
• Boiling Point: 496.6 °C at 760 mmHg
• Flash Point: 254.1 °C
• Appearance: /
• Density: 1.3 g/cm³
• Vapor Pressure: 1.11E-10mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: Keep Cold
• CAS DataBase Reference: N-MORPHOLINYL 3-BORONOBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-MORPHOLINYL 3-BORONOBENZAMIDE(723281-55-8)
• EPA Substance Registry System: N-MORPHOLINYL 3-BORONOBENZAMIDE(723281-55-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 723281-55-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemical Reactions:
N-MORPHOLINYL 3-BORONOBENZAMIDE is used as a reagent for its distinctive reactivity, particularly due to the boron atom, which facilitates a range of chemical transformations in organic synthesis.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, N-MORPHOLINYL 3-BORONOBENZAMIDE serves as a building block for the creation of various organic compounds. Its morpholine ring structure is beneficial for enhancing the solubility and stability of the resulting pharmaceuticals, which is crucial for their efficacy and safety.
Used in Research and Development:
N-MORPHOLINYL 3-BORONOBENZAMIDE is utilized in research for exploring new chemical reactions and developing innovative synthetic pathways, contributing to the advancement of organic chemistry and medicinal chemistry.
Used in Industrial Processes:
N-MORPHOLINYL 3-BORONOBENZAMIDE is also employed in industrial processes where its unique chemical properties are harnessed for the large-scale production of pharmaceuticals and other organic compounds, ensuring efficiency and effectiveness in manufacturing.

InChI:InChI=1/C11H14BNO4/c14-11(13-4-6-17-7-5-13)9-2-1-3-10(8-9)12(15)16/h1-3,8,15-16H,4-7H2

Downstream Products

• 875781-22-9 morpholin-4-yl-[3-(1H-pyrazolo[3,4-b]pyridin-5-yl)-phenyl]-methanone 
• 791-28-6 Triphenylphosphine oxide 
• 1428537-29-4 C₁₇H₁₅N₃O₃S 
• 1617499-01-0 [3-[6-amino-5-(1-isopropyltriazol-4-yl)-3-pyridyl]phenyl]morpholinomethanone 
• 1229457-63-9 (3-{1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridin-6-yl}phenyl)(morpholin-4-yl)methanone 
• 875639-33-1 (3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)(morpholino)-methanone 
• 875635-75-9 (3-(3-(2-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)(morpholino)methanone 
• 927696-01-3 (3-(3-(2,6-dimethoxyphenyl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)(morpholino)methanone 
• 875639-36-4 (3-(3-(2-fluorophenyl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)(morpholino)methanone 
• 875639-35-3 (3-(3-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)-(morpholino)methanone 
• 875639-34-2 (3-(3-iodo-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)(morpholino)-methanone 

Relevant articles and documents

11β-HSD1 INHIBITORS

The invention relates to sulfonamide compounds of formula (I) wherein A, B, R1 and Xl to X3 have the meaning as cited in the description and the claims. For example A is biphenyl, B is 3-methoxyphenyl, Rl is H and Xl to X3 are CH. Said compounds are usefu