723284-71-7Relevant academic research and scientific papers
N-Aryl-γ-lactams as integrin αvβ3 antagonists
Xi, Ning,Arvedson, Stephen,Eisenberg, Shawn,Han, Nianhe,Handley, Michael,Huang, Liang,Huang, Qi,Kiselyov, Alexander,Liu, Qingyian,Lu, Yuelie,Nunez, Gladys,Osslund, Timothy,Powers, David,Tasker, Andrew S.,Wang, Ling,Xiang, Tingjian,Xu, Shimin,Zhang, Jiandong,Zhu, Jiawang,Kendall, Richard,Dominguez, Celia
, p. 2905 - 2909 (2004)
Novel αvβ3 antagonists based on the N-aryl-γ-lactam scaffold were prepared. SAR studies led to the identification of potent antagonists for αvβ3 receptor with excellent selectivity against the structurally relat
