723286-68-8

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE-3-CARBOXYLATE is used as a potential active ingredient or intermediate in the development of new pharmaceutical products. Its complex structure may offer unique properties that can be harnessed for therapeutic applications.
Used in Organic Chemistry Research:
In the field of organic chemistry, ETHYL 5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE-3-CARBOXYLATE is used as a research compound for studying its chemical properties, reactivity, and potential applications in the synthesis of other complex molecules. This can contribute to the advancement of organic chemistry and the discovery of new chemical reactions or processes.

InChI:InChI=1/C8H12N4O2/c1-2-14-8(13)7-11-10-6-5-9-3-4-12(6)7/h9H,2-5H2,1H3

Upstream product

• 723286-66-6 ethyl oxo-(2-pyrazin-2-yl-hydrazino)acetate 

Downstream Products

• 1227934-22-6 N-(6-(4-(2-(2-aminophenyl)acetyl)piperazin-1-yl)pyridin-3-yl)-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)oxazole-5-carboxamide 
• 1227934-10-2 N-[6-(5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl)-3-pyridinyl]-2-(4-phenyl-1-piperidinyl)-4-(trifluoromethyl)-5-oxazolecarboxamide 
• 1227934-07-7 ethyl 5,6,7,8-tetrahydro-7-[5-[[[2-(4-phenyl-1-piperidinyl)-4-(trifluoromethyl)-5-oxazolyl]carbonyl]amino]-2-pyridinyl]-1,2,4-triazolo[4,3-a]pyrazine-3-carboxylate 

Relevant academic research and scientific papers

Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA (sitagliptin phosphate)

A series of β-aminoamides bearing triazolopiperazines has been prepared and evaluated as potent, selective, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. Efforts at optimization of the β-aminoamide series, which ultimately led to the discovery

3-AMINO-4-PHENYLBUTANOIC ACID DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to 3-amino-4-phenylbutanoic acid derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.