72331-38-5

Usage

Type of compound

Heterocyclic compound

Definition of heterocyclic compound

A compound with a ring structure that includes at least two different elements

Usage

Building block in the synthesis of pharmaceuticals and in organic chemistry research

Potential applications

Medicinal chemistry

Reason for potential applications

Ability to bind to various biological targets and diverse pharmacological activities

Importance

Structure and reactivity make it an important intermediate in the development of new drugs and therapeutic agents

Upstream product

• 72331-49-8 5,5-(ethylenedithio)perhydro-1,3-diazepin-2-one 
• 72331-47-6 2-(2-Isocyanato-ethyl)-2-isocyanatomethyl-[1,3]dithiolane 

Downstream Products

• 74024-60-5 1-(2,3,5-Tribenzoyl-β-D-ribofuranosyl)-5-keto-perhydro-1,3-diazepin-2-one 
• 104111-90-2 1-β-D-ribofuranosyl-5-hydroxyperhydro-1,3-diazepin-2-one 

Relevant academic research and scientific papers

Seven-membered ring compounds as inhibitors of cytidine deaminase

Seven-membered heterocyclic nucleosides used to inhibit the deamination enzyme responsible for the inactivation of arabinosylcytosine (ara--C). Preferred nucleosides containing a seven-member aglycone are as follows: STR1 Preferred aglycones are as follow

1,3-Diazepinones. 1. Synthesis of 5-Hydroxyperhydro-1,3-diazepin-2-one

The synthesis of 5-hydroxyperhydro-1,3-diazepin-2-one (3) is accomplished by two different routes.The first route involves the reduction of the precursor ketone 2, which is synthesized in seven steps from levulinic acid (5).The second approach makes use of the hydration of the symmetrically unsaturated precursor 4 via the hydroboration-oxidation procedure.This precursor in turn is obtained by direct cyclization of cis-1,4-diamino-2-butene (12).