723332-74-9Relevant academic research and scientific papers
Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors
, p. 3050 - 3053 (2009)
We discovered a structurally novel SCD (Δ9 desaturase) inhibitor 4a (CVT-11,563) that has 119 nM potency in a human cell-based (HEPG2) SCD assay and selectivity against Δ5 and Δ6 desaturases. This compound has 90% oral bioavailability (rat) and excellent
