72351-69-0Relevant academic research and scientific papers
Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands
Wu, Wen-Lian,Caplen, Mary Ann,Domalski, Martin S.,Zhang, Hongtao,Fawzi, Ahmad,Burnett, Duane A.
, p. 3157 - 3160 (2007/10/03)
A series of aminoalkylazetidines has been discovered as novel ORL1 receptor ligands. Structure-activity relationships have been investigated at the azetidine N and the alkyl side chain sites. Several potent and selective analogues have been identified.
Suppressing obesity and over-secretion of insulin with 2-(α-hydroxy-m-trifluoromethylbenzyl)azetidine
-
, (2008/06/13)
2-(α-hydroxy-m-trifluoromethylbenzyl)azetidine and its physiologically acceptable acid addition salts have antiobesity action as well as suppressive action against oversecretion of insulin.
Novel aminoglycoside derivatives
-
, (2008/06/13)
Novel aminoglycoside derivatives and their salts containing 2-deoxystreptamine moiety, of which the 1-amino group is acylated by a group represented by the formula: STR1 (wherein R is 4 to 6 membered heterocyclic group containing 1 to 2 nitrogen atoms whi
