72398-17-5

Upstream product

• 76951-64-9 methyl 4-O-acetyl-2-O-trityl-α-L-rhamnopyranoside 
• 76951-65-0 methyl 4-O-acetyl-3-O-trityl-α-L-rhamnopyranoside 
• 14686-86-3 methyl 4-O-acetyl-2,3-di-O-isopropylidene-α-L-rhamnopyranoside 
• 53437-43-7 methyl 4-O-acetyl-α-L-rhamnopyranoside 

Relevant academic research and scientific papers

SYNTHESIS OF 1,2-trans-DISACCHARIDES via SUGAR THIO-ORTHOESTERS

The reaction of sugar 1,2-thio-orthoesters in the D-gluco, D-galacto, D-manno, and L-rhamno series with primary and secondary trityl ethers of monosaccharides, in the presence of triphenylmethylium perchlorate as catalyst, affords, stereospecifically, derivatives of 1,2-trans-disaccharides in good yields. 4-Trityl ethers of benzyl 2-acetamido-3,6-di-O-acetyl-2-deoxy-α-D-glucopyranoside and methyl 2,3,6-tri-O-benzoyl-α-D-galactopyranoside exhibit low reactivity in glycosylation by thio-ortho-esters.A reaction scheme for the glycosylation is discussed.