72409-20-2

Basic information

• Product Name: N⁴-benzoyl-5'-O-(tert-butyldimethylsilyl)cytidine
• Synonyms: N⁴-benzoyl-5'-O-(tert-butyldimethylsilyl)cytidine
• CAS NO: 72409-20-2
• Molecular Weight: 461.59
• Mol File: 72409-20-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N⁴-benzoyl-5'-O-(tert-butyldimethylsilyl)cytidine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁴-benzoyl-5'-O-(tert-butyldimethylsilyl)cytidine(72409-20-2)
• EPA Substance Registry System: N⁴-benzoyl-5'-O-(tert-butyldimethylsilyl)cytidine(72409-20-2)

Safety Data

• Hazardous Substances Data: 72409-20-2(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 13089-48-0 N₄-benzoylcytidine 

Downstream Products

• 142068-08-4 Phosphoric acid (2S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester phenyl ester; compound with ammonia 
• 142068-06-2 Phenyl-phosphonothioic acid O-[(2S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl] ester; compound with ammonia 
• 142068-05-1 Phenyl-phosphonic acid mono-[(2S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl] ester; compound with ammonia 
• 142102-28-1 N⁴-5'-O-(tert-butyldimethylsilyl)-2',3'-bis-O-<(methylthio)thiocarbonyl>cytidine 
• 142068-18-6 N⁴-benzoyl-2',3'-didehydro-2',3'-dideoxycytidine 5'-dimethyl phosphate 
• 142068-16-4 N⁴-benzoyl-5'-O-(tert-butyldimethylsilyl)-2',3'-didehydro-2',3'-dideoxycytidine 
• 123413-57-0 N⁴-benzoyl-2',3'-didehydro-2',3'-dideoxycytidine 

Relevant articles and documents

Synthesis of nucleotidylated poliovirus VPg proteins

Phosphitylation of the side chain hydroxyl function of Fmoc protected tyrosine with 5′-phosphoramidites of suitably protected cytidine, adenosine, and guanosine, followed by oxidation gave three novel nucleotidylated amino acid building blocks. After protective group manipulation, these building blocks were used in a solid phase peptide synthesis to afford the nucleotidylated poliovirus proteins VPgpC, VPgpA, and VPgpG.

NITRATE ION AS CATALYST FOR SELECTIVE SILYLATIONS OF NUCLEOSIDES

Nitrate ion has been found to have a remarkable effect on the selectivity of silylation of ribonucleosides using the t-butyldimethylsilyl group.