72410-06-1

Basic information

• Product Name: 2-carbamothioylacetamide
• Synonyms: 2-carbamothioylacetamide;2-Thiocarbamoyl-acetamide
• CAS NO: 72410-06-1
• Molecular Formula: C₃H₆N₂OS
• Molecular Weight: 118.16
• Mol File: 72410-06-1.mol

Chemical Properties

• Boiling Point: 359°C at 760 mmHg
• Flash Point: 170.9°C
• Appearance: /
• Density: 1.35g/cm³
• Vapor Pressure: 2.45E-05mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: 2-carbamothioylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-carbamothioylacetamide(72410-06-1)
• EPA Substance Registry System: 2-carbamothioylacetamide(72410-06-1)

Safety Data

• Hazardous Substances Data: 72410-06-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H6N2OS/c4-2(6)1-3(5)7/h1H2,(H2,4,6)(H2,5,7)

Upstream product

• 109-77-3 malononitrile 
• 107-91-5 cyanoacetic acid amide 
• 64-17-5 ethanol 
• 7783-06-4 hydrogen sulfide 

Downstream Products

• 173739-73-6 2-(4-methyl-thiazol-2-yl)-acetamide 
• 111421-98-8 4-(4-Chloro-phenyl)-6-hydroxy-2-oxo-6-phenyl-piperidine-3-carbothioic acid amide 
• 120353-52-8 2-Thiocarbamoyl-2-(p-tolyl-hydrazono)-acetamide 
• 111422-01-6 4-(4-Nitro-phenyl)-2-oxo-6-phenyl-1,2,3,4-tetrahydro-pyridine-3-carbothioic acid amide 
• 111421-97-7 6-Hydroxy-4,6-diphenyl-3-thiocarbamoyl-3,4,5,6-tetrahydropyridine-2(1H)-one 
• 58351-19-2 2-(4-phenyl-1,3-thiazol-2-yl)acetamide 
• 79927-21-2 4,6-dimethyl-2-mercaptonicotinamide 
• 120353-80-2 5-phenylazo-2,4-dimethylthiazole 

Relevant articles and documents

Unexpected result in the reaction of 3-amino-3-thioxopropanamides with 2-anilinomethylene derivatives of 1,3-dicarbonyl compounds. synthesis of pyrimidine-5-carboxamide derivatives

The interaction of 3-amino-3-thioxopropanamides with 2-anilinomethylene derivatives of dimedone, 1,3-cyclohexanedione and Meldrum's acid led to the formation of 2-(2-amino-2-oxoethyl)-6-thioxo-1,6-dihydropyrimidine-5- carboxamides. The latter were alkylated in alkaline medium with the formation of 4-(alkylthio)pyrimidine-5-carboxamide derivatives.

Heterocyclen-Synthesen mit Monothiomalonsaeure-Amiden: Synthese von 3-Oxo-2,3-dihydroisothiazolopyridinen und 3-Oxo-2,3-dihydroisothiazolopyrimidinen

The monothiomalonic acid amides 5, prepared from cyanoacetamides 4 and hydrogen sulphide, react with diketones 6 or aldehyde derivatives 7 to give the 2-thioxo-1,2-dihydropyridine-3-carboxamides 8 which can be cyclised to the 3-oxo-2,3-dihydroisothiazolo