72428-40-1Relevant academic research and scientific papers
PRODUCTION OF 2,4-DISUBSTITUTED 1,3,5-TRIAZINES ON THE BASIS OF N-2,2-DICHLOROVINYLBENZIMIDOYL CHLORIDE AND ITS ANALOGS
Popovich, T.P.,Drach, B.S.
, p. 2158 - 2164 (2007/10/02)
Treatment of the products from the condensation of N-2,2-dichlorvinylbenzimidoyl chloride and its analogs with amidines at first with chlorine and then with sodium bicarbonate leads to 2,4,6-trisubstituted derivatives of dihydro-1,3,5-triazine containing
Ring Transformations and Amination in Reactions of 3-Halogeno-5-phenyl-1,2,4-triazines with Potassium Amide in Liquid Ammonia
Rykowski, A.,Plas, H. C. van der
, p. 881 - 885 (2007/10/02)
The reactions of 3-X-5-phenyl-1,2,4-triazines (X = fluoro, chloro, bromo, iodo) toward potassium amide/liquid ammonia were studied.Whereas the 3-fluoro compound gives only the 3-amino derivative, the 3-chloro, 3-bromo, and 3-iodo compounds yield a complex mixture containing, besides 3-amino-5-phenyl-1,2,4-triazine and 5-phenyl-1,2,4-triazine, ring transformation products, i.e., 3,5-diphenyl-1,2,4-triazine, 2,4-diphenyl-1,3,5-triazine, 6-amino-2,4-diphenyl-1,3,5-triazine, and 3-X-5-phenyl-1,2,4-triazole.Evidence is found that in the ring transformation of 3-X-5-phenyl-1,2,4-triazines into 2,4-diphenyl-1,3,5-triazines, benzamidine must be an intermediate.The mechanisms of the amination and ring transformation are extensively discussed.
