72431-21-1

Basic information

• Product Name: 1,4-Cyclohexadiene-1-carboxylicacid,ethylester(9CI)
• Synonyms: 1,4-Cyclohexadiene-1-carboxylicacid,ethylester(9CI);1,4-Cyclohexadiene-1-carboxylic Acid Ethyl Ester
• CAS NO: 72431-21-1
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.19
• Product Categories: CARBOXYLICESTER;Intermediates;Miscellaneous Reagents
• Mol File: 72431-21-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: 1,4-Cyclohexadiene-1-carboxylicacid,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Cyclohexadiene-1-carboxylicacid,ethylester(9CI)(72431-21-1)
• EPA Substance Registry System: 1,4-Cyclohexadiene-1-carboxylicacid,ethylester(9CI)(72431-21-1)

Safety Data

• Hazardous Substances Data: 72431-21-1(Hazardous Substances Data)

Usage

Chemical Properties

Clear Colourless Oil

Uses

Intermediate in the preparation of D,L-Gabaculine.

Upstream product

• 64-17-5 ethanol 
• 4315-35-9 cyclohexa-1,4-diene-1-carboxylic acid 
• 106-99-0 buta-1,3-diene 
• 623-47-2 propynoic acid ethyl ester 
• 72431-18-6 1-(morpholin-4-yl)prop-2-yn-1-one 
• 368-39-8 triethyloxonium fluoroborate 

Downstream Products

• 59556-15-9 5-(tert-butoxycarbonylamino)-1,3-cyclohexadienecarboxylic acid 
• 1377828-50-6 C₁₁H₁₅NO₄ 
• 72431-22-2 C₁₀H₁₂INO₃ 
• 72431-23-3 C₁₀H₁₂INO₃ 
• 1377828-51-7 C₁₃H₁₉NO₄ 
• 72431-24-4 C₁₄H₂₂INO₄ 
• 72431-25-5 C₁₄H₂₂INO₄ 
• 72431-26-6 ethyl 5-(tert-butoxycarbonylamino)-cyclohexa-1,3-diene-1-carboxylate 

Relevant articles and documents

CATALYST AND PROCESS FOR SYNTHESISING THE SAME

The invention relates to a method for synthesising tethered ruthenium catalysts and novel tethered ruthenium catalysts obtainable by this methods. The method involves carrying out an "arene swapping" reaction avoiding the requirement to use complicated techniques making use of unreliable Birch reductions and unstable cyclodienyl intermediates.

Efficient preparation of the key intermediate in corey's tamiflu synthesis

A very efficient two-step synthesis was developed to prepare the key intermediate in Corey's Tamiflu synthesis. DBU (1,8-diazabicyclo[5.4.0] undec-7-ene) was used as a multifunctional catalyst for a series of reactions in a one pot procedure. The new synthesis was featured by the good availability of the starting material and the ease of the synthetic steps. This method might be practical for large scale preparations. A very efficient two-step synthesis was developed to prepare the key intermediate in Corey's Tamiflu synthesis. DBU was used as a multifunctional catalyst for a series of reactions in a one pot procedure. The new synthesis was featured by the good availability of the starting material and the ease of the synthetic steps. This method might be practical for large scale preparations.