72432-13-4Relevant academic research and scientific papers
Synthesis of N-[4-(2'-[18F]fluoroalkoxybenzoyl)]- And N-(3-[123I]iodo-4-methoxybenzoyl)pyrrolidin-2-ones as potential brain imaging agents
Akula, Murthy,Blevins, David,Kabalka, George W.,Osborne, Dustin
, p. 1226 - 1236 (2019/07/31)
– The microfluidic synthesis of promising brain imaging PET agents N-[4-(2’-[18F]fluoroalkyloxybenzoyl)]pyrrolidin-2-ones 13a-c was accomplished by nucleophilic radiofluorination of the corresponding tosylate precursors 9a-c with Kryptofix-pota
1-(P-Methoxy p-hydroxy, and p-benzyloxy benzoyl)-2-pyrrolidinones
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, (2008/06/13)
1-(p-methoxybenzoyl)-2-pyrrolidinone and intermediates useful in its preparation are described. The 1-(p-methoxybenzoyl)-2-pyrrolidinone is useful in the prevention of cerebral insufficiency.
Syntheses and Reactions of (Trimethylsiloxy)benzoyl Chlorides
Schwarz, Gerd,Alberts, Heinrich,Kricheldorf, Hans R.
, p. 1257 - 1270 (2007/10/02)
The (trimethylsiloxy)benzoyl chlorides 1-7 are easily to obtain under mild conditions from silylated hydroxybenzoic acids by means of thionyl chloride.Whereas these acid chlorides are stable at room temperature, they undergo condensation polymerisation at temperatures above 100 deg C.Reactions with various nucleophils, such as thioalcohols, phenols, amines, N,O-bis(silylated)amino acids and N-silylated lactams were investigated.With hexamethyldisilazane and thionyl chloride the (trimethylsiloxy)benzonitriles 21, 22 are accessible, and by means of trimethylsilylazide the (trimethylsiloxy)phenyl isocyanates 23-25 were obtained.Conversion with phenyl carbazate and subsequent silylation lead to the 2-(trimethylsiloxy)phenyl-1,3,4-oxadiazol-5-ones 27a-c.
