724433-59-4

Upstream product

• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 724433-53-8 4-benzyloxy-3-diphenylphosphinoyl-2-(4-methoxybenzyl)-2,3-dihydro-1H-isoindol-1-one 
• 724433-56-1 3-benzyloxy-N-diphenylphosphinoylmethyl-2-methoxy-N-(4-methoxybenzyl)benzamide 

Downstream Products

• 724433-50-5 (Z)-3-(6-bromobenzo[1,3]dioxol-5-ylmethylene)-4-hydroxy-2-(4-methoxybenzyl)-2,3-dihydro-1H-isoindol-1-one 

Relevant academic research and scientific papers

A new route to aristocularine alkaloids: Total synthesis of aristoyagonine

A short and efficient synthesis of aristocularines, involving the sequential construction of phosphorylated 4-alkoxyisoindolinones, Horner-type reaction, and ultimate cyclization by diaryl ether coupling, is disclosed. The success of this new conceptual a

Crystal structure of 4-benzyloxy- and 4-hydroxy- (Z)-3-[(6-bromo-1, 3-benzodioxol-5-yl)methylene]-2-(4-methoxybenzyl)-2,3-dihydro-1H-isoindol-1-ones

In contrast to unsubstituted models, the Horner reaction between phosphorylated 4-benzyloxyisoindolinone and ortho-bromobenzaldehyde gives rise selectively to the arylmethylene derivative with a Z-configuration.