72448-17-0

Basic information

• Product Name: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE
• Synonyms: tetrachlorothiophene1,1-dioxide;tetrachlorothiophenedioxide;2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE
• CAS NO: 72448-17-0
• Molecular Formula: C₄Cl₄O₂S
• Molecular Weight: 253.92
• Mol File: 72448-17-0.mol

Chemical Properties

• Boiling Point: 218.2°C at 760 mmHg
• Flash Point: 85.8°C
• Appearance: /
• Density: 1.97g/cm³
• Vapor Pressure: 0.188mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE(72448-17-0)
• EPA Substance Registry System: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE(72448-17-0)

Safety Data

• Hazardous Substances Data: 72448-17-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C4Cl4O2S/c5-1-2(6)4(8)11(9,10)3(1)7

Upstream product

• 6012-97-1 2,3,4,5-tetrachlorothiophene 

Downstream Products

• 72448-16-9 1,2,3,4-Tetrachloro-5-hept-6-enyl-cyclohexa-1,3-diene 
• 72541-85-6 (2,3,4,5-tetrachlorophenyl)acetaldehyde 
• 72541-81-2 C₁₂H₄Cl₈O₃S 
• 72541-70-9 1-(2,3,4,5-Tetrachloro-phenyl)-propan-2-one 
• 72541-83-4 2-(2,3,4,5-tetrachloro-2,4-cyclohexadienyl)furan 
• 72541-79-8 methyl (2,3,4,5-tetrachlorophenyl)acetate 
• 72541-72-1 2,3,4,5-tetrachloro-6-methylphenylacetone 
• 72524-46-0 1,2,3,4-tetrachloro-1,3-cyclohexadiene-5,6-dicarboxylic acid anhydride 
• 72541-71-0 1-(2,3,4,5-Tetrachloro-phenyl)-hexan-2-one 
• 72541-78-7 (E)-3-Hydroxy-4-(2,3,4,5-tetrachloro-phenyl)-but-3-en-2-one 
• 72541-82-3 (2,3,4,5-tetrachloro-6-methylphenyl)acetic acid 
• 72524-56-2 1-(2,3,4,5-Tetrachloro-cyclohexa-2,4-dienyl)-pyrrolidin-2-one 
• 72541-77-6 methyl 2-hydroxy-3-(2,3,4,5-tetrachlorophenyl)acrylate 
• 72541-75-4 Acetic acid 2-oxo-3-(2,3,4,5-tetrachloro-phenyl)-propyl ester 

Relevant articles and documents

A novel method for the oxidation of thiophenes. Synthesis of thiophene 1,1-dioxides containing electron-withdrawing substituents

A novel method for the synthesis of thiophene 1,1-dioxides by oxidation of substituted thiophenes with trifluoroperoxyacetic acid was developed. The effect of the solvent nature on the course of the reaction was studied and optimum conditions for the oxid

Azepine- or Azocine-Embedded Hexabenzocoronene Derivatives as Nitrogen-Doped Saddle or Saddle-Helix Nanographenes

Two novel nitrogen-doped, hexa-peri-hexabenzocoronene (HBC)-based nanographenes (NGs) 1 and 2 bearing an azepine and an azocine at the fjord region, respectively, were synthesized and characterized. Notably, structure 1 was synthesized by Diels–Alder reac

Sulfur dioxide prodrugs: Triggered release of SO2 via a click reaction

Sulfur dioxide (SO2) is being recognized as a possible endogenous gasotransmitter with importance on par with that of NO, CO, and H2S. Herein we describe a series of SO2 prodrugs that are activated for SO2 relea

Octachloroazulene

The title compound, the first perhaloazulene, has been synthesized from hexachlorobutadiene and cyclopentadiene. Further chlorination of 1,3,4,5,6,7-hexachloroazulene results in addition, rot substitution, under electrophilic as well as free radical conditions. Radical chlorination of the hexachloro-azulene affords in good yield a single decachlorotetrahydroazulene. Treatment of this Cl10 compound with one equiv of a phosphazene base gives a nonachlorodihydroazulene, but the addition of a second equiv results in dechlorination to 1,2,3,4,5,6,7-heptachloroazulene as well as dehydrochlorination to octachloro-azulene. The former azulene is obtained cleanly from the Cl9 compound with acid catalysis or by reduction with mercury. In the presence of calcium carbonate, however, the Cl9 intermediate yields the dark green octachloroazulene. Although octachloronaphthalene is readily converted into its octafluoro counterpart, the isomeric octachloroazulene is far too sensitive to undergo the analogous transformation.

Annelations with Tetrachlorothiophene 1,1-Dioxide

Tetrachlorothiophene 1,1-dioxide is a reactive, cheletropic Diels-Alder reagent.It has been used to annelate, with loss of sulfur dioxide, a large variety of olefinic compounds to form 1,2,3,4-tetrachloro-1,3-cyclohexadiene derivatives.Dehydrochlorination of these forms 1,2,4-trichloro aromatic compounds.Both double bonds in thiophene and N-methylpyrrole are annelated.Addition of tetrachlorothiophene dioxide to acyclic 1,5-dienes, which may contain a heteroatom, provides a facile synthesis of tetrachloroisotwistenes (51) and heteroisotwistenes (56) by a double Diels-Alder reaction.Acyclic 1,6-dienes lead to tetrachlorohomoisotwistene (59) and heterohomoisotwistenes (61).By use of 1,5-cyclooctadiene, sym-dibenzocyclooctatetraene, and 1,5-cyclononadiene, the more complex carbocycles 62, 65, and 66 are generated.Tetrabromothiophene dioxide reacts like the tetrachloro compound.