72448-17-0

Basic information

• Product Name: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE
• Synonyms: tetrachlorothiophene1,1-dioxide;tetrachlorothiophenedioxide;2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE
• CAS NO: 72448-17-0
• Molecular Formula: C₄Cl₄O₂S
• Molecular Weight: 253.92
• Mol File: 72448-17-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 218.2°C at 760 mmHg
• Flash Point: 85.8°C
• Appearance: /
• Density: 1.97g/cm³
• Vapor Pressure: 0.188mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE(72448-17-0)
• EPA Substance Registry System: 2,3,4,5-TETRACHLOROTHIOPHENE 1,1-DIOXIDE(72448-17-0)

Safety Data

• Hazardous Substances Data: 72448-17-0(Hazardous Substances Data)

Usage

Uses

Tetrachlorothiophene dioxide is an intermediate in the synthesis of 1,2,3,4,6-Pentachloronaphthalene (P237530), which is a standard for environmental testing and research and a substance for the discriminant analysis for activation of aryl hydrocarbon receptor by polychlorinated naphthalenes.

InChI:InChI=1/C4Cl4O2S/c5-1-2(6)4(8)11(9,10)3(1)7

Upstream product

• 6012-97-1 2,3,4,5-tetrachlorothiophene 

Downstream Products

• 72541-85-6 (2,3,4,5-tetrachlorophenyl)acetaldehyde 
• 72541-81-2 C₁₂H₄Cl₈O₃S 
• 72541-70-9 1-(2,3,4,5-Tetrachloro-phenyl)-propan-2-one 
• 72541-83-4 2-(2,3,4,5-tetrachloro-2,4-cyclohexadienyl)furan 
• 72541-79-8 methyl (2,3,4,5-tetrachlorophenyl)acetate 
• 72541-72-1 2,3,4,5-tetrachloro-6-methylphenylacetone 
• 72541-71-0 1-(2,3,4,5-Tetrachloro-phenyl)-hexan-2-one 
• 72541-78-7 (E)-3-Hydroxy-4-(2,3,4,5-tetrachloro-phenyl)-but-3-en-2-one 
• 72541-82-3 (2,3,4,5-tetrachloro-6-methylphenyl)acetic acid 
• 72524-56-2 1-(2,3,4,5-Tetrachloro-cyclohexa-2,4-dienyl)-pyrrolidin-2-one 
• 72541-77-6 methyl 2-hydroxy-3-(2,3,4,5-tetrachlorophenyl)acrylate 
• 72541-75-4 Acetic acid 2-oxo-3-(2,3,4,5-tetrachloro-phenyl)-propyl ester 
• 72541-76-5 N-[2-Oxo-3-(2,3,4,5-tetrachloro-phenyl)-propyl]-acetamide 
• 72524-52-8 5-(2,3,4,5-Tetrachloro-cyclohexa-2,4-dienylmethyl)-benzo[1,3]dioxole 

Relevant articles and documents

A novel method for the oxidation of thiophenes. Synthesis of thiophene 1,1-dioxides containing electron-withdrawing substituents

A novel method for the synthesis of thiophene 1,1-dioxides by oxidation of substituted thiophenes with trifluoroperoxyacetic acid was developed. The effect of the solvent nature on the course of the reaction was studied and optimum conditions for the oxid

Sulfur dioxide prodrugs: Triggered release of SO2 via a click reaction

Sulfur dioxide (SO2) is being recognized as a possible endogenous gasotransmitter with importance on par with that of NO, CO, and H2S. Herein we describe a series of SO2 prodrugs that are activated for SO2 relea

Annelations with Tetrachlorothiophene 1,1-Dioxide

Tetrachlorothiophene 1,1-dioxide is a reactive, cheletropic Diels-Alder reagent.It has been used to annelate, with loss of sulfur dioxide, a large variety of olefinic compounds to form 1,2,3,4-tetrachloro-1,3-cyclohexadiene derivatives.Dehydrochlorination of these forms 1,2,4-trichloro aromatic compounds.Both double bonds in thiophene and N-methylpyrrole are annelated.Addition of tetrachlorothiophene dioxide to acyclic 1,5-dienes, which may contain a heteroatom, provides a facile synthesis of tetrachloroisotwistenes (51) and heteroisotwistenes (56) by a double Diels-Alder reaction.Acyclic 1,6-dienes lead to tetrachlorohomoisotwistene (59) and heterohomoisotwistenes (61).By use of 1,5-cyclooctadiene, sym-dibenzocyclooctatetraene, and 1,5-cyclononadiene, the more complex carbocycles 62, 65, and 66 are generated.Tetrabromothiophene dioxide reacts like the tetrachloro compound.