72457-81-9

Upstream product

• 1452-34-2 2α-bromo-5α-cholestan-3-one 
• 566-88-1 dihydrocholesterone 
• 100-58-3 phenylmagnesium bromide 
• 104759-28-6 3β-hydroxy-10.13-dimethyl-17β-((R)-1.5-dimethyl-hexyl)-3α-phenyl-5α-gonane 
• 104759-97-9 3α-hydroxy-10.13-dimethyl-17β-((R)-1.5-dimethyl-hexyl)-3β-phenyl-5α-gonane 
• 591-51-5 phenyllithium 
• 96687-16-0 (5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-3-phenyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol 
• 143-66-8 sodium tetraphenyl borate 

Downstream Products

• 88446-82-6 3β-Phenyl-5α-cholestan-2α-ol 
• 106405-69-0 2α.3α-Dibrommethylen-3β-phenyl-cholestan 
• 156177-50-3 Oxo-phenyl-acetic acid (2R,3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-3-phenyl-hexadecahydro-cyclopenta[a]phenanthren-2-yl ester 
• 156177-53-6 (R)-2-Hydroxy-2-phenyl-butyric acid (2R,3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-3-phenyl-hexadecahydro-cyclopenta[a]phenanthren-2-yl ester 

Relevant academic research and scientific papers

Novel Steroidal Chiral Auxiliaries: Enantioselective Synthesis of Chiral α-Hydroxy Acids

The synthesis is reported of three novel steroidal chiral auxiliaries (4) which were used to generate an α-hydroxy acid in high optical purity (90-98percent ee).

Palladium-Catalyzed Cross-Coupling Reactions of Vinyl and Aryl Triflates with Tetraarylborates

Sodium tetraarylborates 2 have been found to couple efficiently with vinyl and aryl triflates 1 in the presence of a palladium(0) catalyst to afford arylalkenes and biaryls 3 in good yields and under mild conditions.

p-Toluenesulfonic Acid Adsorbed on Silica Gel: An Efficient Dehydrating Agent of Alcohols

Secondary and tertiary alcohols are efficiently dehydrated by reaction with p-toluenesulfonic acid supported on silica gel.In particular, the procedure allows the direct conversion of 3-hydroxy-steroids into Δ2-olefins or Δ3,5-dienes, without passing through the mesylate or tosylate esters.

SYNTHESIS AND LIQUID CRYSTAL PROPERTIES OF SOME 3-ARYLCHOLEST-2-ENES AND 3-ARYLCHOLEST-3,5-DIENES.

A series of mesogenic 3-arylcholest-2-enes and 3-arylcholest-3,5-dienes were prepared. All members of the monoene and diene steroid series exhibited enantiotropic cholesteric mesophases. The broadest mesophase range was 90 degree , found for para-methoxyphenylcholest-2-ene.