724702-24-3Relevant articles and documents
Asymmetric sulfur ylide based enantioselective synthesis of D-erythro-sphingosine
Morales-Serna, Jose Antonio,Llaveria, Josep,Diaz, Yolanda,Matheu, M. Isabel,Castillon, Sergio
supporting information; experimental part, p. 4502 - 4504 (2009/03/12)
An asymmetric sulfur ylide reaction was employed to prepare an epoxide intermediate in a convergent manner. This epoxide was efficiently transformed into D-erythro-sphingosine.
Highly Diastereoselective Synthesis of D-threo- and D-erythro-Sphingosine from Glycidol
Katsumura, Shigeo,Yamamoto, Noriyoshi,Fukuda, Etsuko,Iwama, Seiji
, p. 393 - 394 (2007/10/02)
D-Threo- and D-erythro-sphingosine, (1) and (2), inhibitors of protein kinase C, have been efficiently synthesized from glycidol through (R)-4-methoxycarbonyloxazolidinone (3) by selective mono-alkylation followed by highly diastereoselective reduction of the tin-substituted pentadecenyl ketone 5.