72472-29-8Relevant academic research and scientific papers
Generation of cycloheptynes and cyclooctynes via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates
Yoshida, Suguru,Karaki, Fumika,Uchida, Keisuke,Hosoya, Takamitsu
supporting information, p. 8745 - 8748 (2015/05/20)
Cycloheptynes and cyclooctynes were efficiently generated via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates. Cycloadditions between various ynophiles and the cycloalkynes generated by this method proceeded
Tetrahydrobenzindole derivatives
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, (2008/06/13)
Compounds containing tetrahydrobenzindole which bind to serotonin receptor and are useful in treatment or prevention of disease induced by abnormality of central peripheral serotonin controlling functions.
General Photoisomerization Approach to trans-Benzobicyclooctenes: Synthetic and Mechanistic Studies
Smith, Amos B.,Wood, John L.,Keenan, Terence P.,Liverton, Nigel,Visnick, Melean
, p. 6652 - 6666 (2007/10/02)
The preparation and photoisomerization of cis-bicyclooctenes (+)-3, 16, and 21-23 are described.For the benzannulated substrates, the primary photochemical events established photostationary states between the cis isomers and the trans-fused cyclop
Bridged-ring Nitrogen Compounds. Part 7. Synthesis of the 1,4-Ethano-3-benzazepine Ring System
Sedgeworth, Janette,Proctor, George R.
, p. 2677 - 2688 (2007/10/02)
9-Bromobenzosuberone was converted via 9-cyanobenzosuberone into several other 9-substituted benzosuberones, but attemps to cause them to cyclise to the tricyclic 1,4-ethano-3-benzazepine ring system were unsuccessful.Both ethyl phenylacetate and ethyl 3-methoxyphenylacetate were converted by conventional procedures into the corresponding 6,7,8,9-tetrahydro-5-methyl-9,10-dioxo-5,8-methano-5H-benzocycloheptenes.The 3-methoxy derivative was further converted into N-benzyl-8-bromo-6,7,8,9-tertrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide which could be converted into the tricyclic 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-2,5-dioxo-1,4-ethano-1H-3-benzazepine and thence in two steps into both 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine and 3-benzyl-2,3,4,5-tetrahydro-8-hydroxy-1-methyl-1,4-ethano-1H-3-benzazepine.Also prepared were 3-benzyl-2,3,4,5-tetrahydro-5-hydroxy-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine and 3-benzyl-3,4-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-5(2H)-one.
