72500-25-5

Usage

Uses

Used in Pharmaceutical Industry:
(S)-1-CBZ-2-CYANOMETHYLPYRROLIDINE is used as a building block for the synthesis of various pharmaceuticals due to its ability to contribute to the creation of complex molecular structures with specific chiral properties. (S)-1-CBZ-2-CYANOMETHYLPYRROLIDINE is instrumental in the development of new drugs and drug intermediates, enhancing the industry's capacity to produce effective and targeted medications.
Used in Agrochemical Industry:
In the agrochemical sector, (S)-1-CBZ-2-CYANOMETHYLPYRROLIDINE serves as a key component in the synthesis of bioactive molecules for use in pesticides and other agricultural chemicals. Its chiral nature allows for the development of more precise and effective compounds that can target specific pests while minimizing harm to non-target organisms and the environment.
Used in Organic Synthesis:
(S)-1-CBZ-2-CYANOMETHYLPYRROLIDINE is utilized as a versatile reagent in organic synthesis, where its unique structure and reactivity contribute to the formation of a wide range of chemical compounds. This makes it an indispensable tool for researchers and chemists working on the development of novel organic compounds for various applications.

InChI:InChI=1/C14H16N2O2/c15-9-8-13-7-4-10-16(13)14(17)18-11-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-8,10-11H2/t13-/m0/s1

Upstream product

• 151-50-8 potassium cyanide 
• 123803-29-2 (S)-benzyl 2-((methylsulfonyloxy)methyl)pyrrolidine-1-carboxylate 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 501-53-1 benzyl chloroformate 
• 6216-63-3 N-Cbz-Prolinol 
• 143-33-9 sodium cyanide 
• 72500-24-4 (2S)-2-(4-methylphenylsulfonyloxymethyl)-pyrrolidine-1-carboxylic acid benzyl ester 

Downstream Products

• 851394-29-1 2-(1H-tetrazol-5-ylmethyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 1166995-46-5 (S,Z)-benzyl 2-(2-amino-2-(hydroxyimino)ethyl)pyrrolidine-1-carboxylate 
• 851394-30-4 5-[(S)-1-pyrrolidin-2-ylmethyl]-1H-tetrazole 
• 56633-75-1 (S)-2-(pyrrolidin-2-yl)acetic acid 

Relevant academic research and scientific papers

Synthesis of homoproline analogues containing heterocyclic rings and their activity as organocatalysts for Michael reaction

Two homoproline derivatives containing either the 5-thioxo-1,2,4-oxadiazole or the 2-oxo-1,2,3,5-oxathiodiazole bioisosteric groups, in replacement of the carboxyl group, were synthesized and their catalytic activities in Michael reactions were evaluated.

A homo-proline tetrazole as an improved organocatalyst for the asymmetric Michael addition of carbonyl compounds to nitro-olefins

A new homo-proline tetrazole derivative 7 has been prepared and shown to have improved properties for achieving asymmetric Michael addition of carbonyl compounds to nitro-olefins.

Synthesis of tetradentate bisamino-bisthiol complexes of oxorhenium(V) as structural mimics of steroids

Two tetradentate chelate systems have been synthesized in order to prepare metal complexes with oxorhenium(V) whose structures will mimic that of steroids. The chelate system with amide/amine/thioether/thiol donor sites failed to give a stable complex, bu

THE SYNTHESIS OF (-)-ISORETRONECANOL, (-)-TRACHELANTHAMIDINE, AND (-)-SUPINIDINE FROM (S)-PROLINE

Dieckmann cyclisation of (S)-N,2-di(carboethoxymethyl)pyrrolidine, made from (S)-proline, gave (8S)-1-carboethoxypyrrolizidin-2-one, which was then converted into (-)-isoretronecanol, (-)-trachelanthamidine, and (-)-supinidine.