7252-78-0

Basic information

• Product Name: 2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
• CAS NO: 7252-78-0
• Molecular Formula: C₁₃H₁₃N₃
• Molecular Weight: 211.2624
• Mol File: 7252-78-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 309.3°C at 760 mmHg
• Flash Point: 166.4°C
• Density: 1.224g/cm³
• Vapor Pressure: 0.000646mmHg at 25°C
• Refractive Index: 1.656
• CAS DataBase Reference: 2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine(7252-78-0)
• EPA Substance Registry System: 2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine(7252-78-0)

Safety Data

• Hazardous Substances Data: 7252-78-0(Hazardous Substances Data)

Upstream product

• 100-47-0 benzonitrile 
• 2941-23-3 2-amino-1-cyanocyclopentene 
• 111-69-3 hexanedinitrile 

Relevant articles and documents

Temperature controlled condensation of nitriles: Efficient and convenient synthesis of β-enaminonitriles, 4-aminopyrimidines and 4-amidinopyrimidines in one system

A series of β-enaminonitriles, 4-aminopyrimidines and 4-amidinopyrimidines were synthesized by condensation of organonitriles in one system. A wide variety of compounds were obtained in good to excellent yields by simply controlling the reaction temperature. The base-induced transformation process is easy for production. The scope and versatility of the method have been successfully demonstrated with 72 examples. The flexible and diversified characteristics of nitriles were introduced based on electronic effect, steric effect, position of substituted groups and intermolecular hydrogen bonding. An updated reaction mechanism is proposed based on the study of the stoichiometric reaction conditions at variable temperature, and on the investigation of products with cis-trans configuration transformation.