725213-56-9Relevant academic research and scientific papers
Synthesis of polycyclic aromatic iodides via ICI-induced intramolecular cyclization
Yao, Tuanli,Campo, Marino A.,Larock, Richard C.
, p. 2677 - 2680 (2004)
The reaction of 2-(arylethynyl)biphenyls with ICI at -78°C affords substituted polycyclic aromatic iodides in good to excellent yields. The aryl substituents can be either electron-donating or electron-withdrawing groups such as OMe, Me, CHO, CO2Et or NO2 groups. This chemistry has been successfully extended to systems containing a variety of polycyclic and heterocyclic rings.
Synthesis of polycyclic aromatics and heteroaromatics via electrophilic cyclization
Yao, Tuanli,Campo, Marino A.,Larock, Richard C.
, p. 3511 - 3517 (2007/10/03)
(Chemical Equation Presented) A variety of substituted polycyclic aromatics are readily prepared in good to excellent yields under very mild reaction conditions by the reaction of 2-(1-alkynyl)biphenyls with ICl, I2, NBS, and p-O2NC
Synthesis of fused polycycles by 1,4-palladium migration chemistry
Huang, Qinhua,Campo, Marino A.,Yao, Tuanli,Tian, Qingping,Larock, Richard C.
, p. 8251 - 8257 (2007/10/03)
Novel palladium migration/arylation methodology for the synthesis of complex fused polycycles has been developed, in which one or more sequential Pd-catalyzed intramolecular migration processes involving C-H activation are employed. The chemistry works best with electron-rich aromatics, which is in agreement with the idea that these palladium-catalyzed C-H activation reactions parallel electrophilic aromatic substitution.
