725228-76-2

Upstream product

• 186581-53-3 diazomethane 
• 725228-74-0 phenyl 2,3-di-O-benzoyl-1-thio-β-D-glucopyranosiduronic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 138857-50-8 phenyl 2,3-bis-O-benzoyl-1-thio-β-D-glucopyranoside 

Downstream Products

• 920508-52-7 methyl 2,3-di-O-benzoyl-1-deoxy-4-O-levulinoyl-1-(phenylsulfanyl)-β-D-glucopyranosyluronate 
• 1158797-00-2 methyl (phenyl 2,3-di-O-benzoyl-4-[4,6-O-di-tert-butylsilylidene-3-O-levulinoyl-2-N-trichloroacetamido-β-D-glucopyranosyl]-1-thio-β-D-glucopyranosyl uronate) 
• 1319721-59-9 methyl (phenyl 2,3-di-O-benzoyl-4-O-methyl-1-thio-β-D-glucopyranoside)uronate 
• 1319721-60-2 methyl (2,3-di-O-benzoyl-4-O-methyl-α-D-glucopyranose)uronate 
• 1384958-23-9 methyl (phenyl 2,3-di-O-benzoyl-4-[4,6-O-di-tert-butylsilylidene-3-O-levulinoyl-2-N-trifluoroacetamido-β-D-glucopyranosyl]-1-thio-β-D-glucopyranosyl uronate) 
• 1384958-24-0 methyl (phenyl 2,3-di-O-benzoyl-4-[4,6-O-di-tert-butylsilylidene-3-O-levulinoyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-1-thio-β-D-glucopyranosyl uronate) 
• 1319721-65-7 methyl (2,3-dibenzoyl-4-O-(4,6-O-di-tert-butylsilandiyl-2-deoxy-3-O-levulinoyl-2-trichloroacetamido-β-D-glucopyranosyl)-β-D-glucopyranoside N-phenyl-2,2,2-trifluoroacetimidate)uronate 
• 920508-62-9 pent-4-enyl (methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->4)-N,N-diacetyl-2-amino-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 920508-67-4 pent-4-enyl (methyl 2,3-di-O-benzoyl-β-D-glucopyranosyluronate)-(1->4)-N,N-diacetyl-2-amino-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 920508-64-1 methyl 2,3-di-O-benzoyl-1-deoxy-4-O-levulinoyl-1-(phenylsulfinyl)-β-D-glucopyranosyluronate 
• 946390-56-3 3-azidopropyl (methyl (2,3-di-O-benzoyl-β-D-glucopyranosid) uronate) 

Relevant academic research and scientific papers

A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates

The synthesis of hyaluronan dimers and tetramers equipped with a 4-methylumbelliferyl group at the reducing end to potentially allow monitoring of hyaluronidase activities is described. The 4-OH at the non-reducing glucuronate in the presented series is either removed or methylated to prohibit transglycosylase reactions, leading to a total of four probes.

Thioglycuronides: Synthesis and application in the assembly of acidic oligosaccharides

Partially protected thioglycuronic acids are prepared efficiently by chemo- and regioselective oxidation of the corresponding thioglycosides using the TEMPO/BAIB reagent combination. After esterification, the thioglycuronic acids proved to be useful as both donor and acceptor in sulfonium-mediated condensations toward acidic di- and trisaccharides.