725229-84-5Relevant academic research and scientific papers
DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF
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Page/Page column 21; 35, (2010/02/12)
Compounds of formula: wherein R1, R2, and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in p
DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF
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Page 42, (2008/06/13)
Compounds of general formula: wherein R1, R2, R3, R4, and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prep
PHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS
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Page 39, (2010/02/07)
Compounds of general formula: wherein R1, R2 and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
N,N-diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: A novel, exceptionally selective, potent δ opioid receptor agonist with oral bioavailability and its analogues
Wei,Brown,Takasaki,Plobeck,Delorme,Zhou,Yang,Jones,Gawell,Gagnon,Schmidt,Yue,Walpole,Payza,St-Onge,Labarre,Godbout,Jakob,Butterworth,Kamassah,Morin,Projean,Ducharme,Roberts
, p. 3895 - 3905 (2007/10/03)
The design, synthesis, and pharmacological evaluation of a novel class of δ opioid receptor agonists, N,N-diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide (6a) and its analogues, are described. These compounds, formally derived from SNC-80 (2) by repl
