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1,3-bis(2-cyanoethyl)urea, also known as BCNU or carmustine, is a nitrosourea-based chemotherapeutic agent. It is a bifunctional alkylating agent that works by cross-linking DNA strands, thereby inhibiting DNA replication and transcription, ultimately leading to cell death. BCNU is primarily used to treat various types of brain tumors, including glioblastoma multiforme, and is also used in the treatment of Hodgkin's lymphoma and other cancers. The chemical structure consists of a urea molecule with two cyanoethyl groups attached to the nitrogen atoms at the 1 and 3 positions, which contribute to its alkylating properties. Due to its potent cytotoxic effects, BCNU is administered in carefully controlled doses and is typically used in combination with other chemotherapy drugs.

7253-99-8

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7253-99-8 Usage

Appearance

White crystalline solid

Solubility

Soluble in water and organic solvents

Uses

a. Cross-linking agent in adhesives, resins, and coatings
b. Curing agent for epoxy resins
c. Flame retardant in polyurethane foams
d. Stabilizer and inhibitor in the synthesis of pharmaceuticals, pesticides, and dyes

Safety concerns

Toxic, may cause skin and eye irritation, respiratory and digestive issues if ingested or inhaled

Check Digit Verification of cas no

The CAS Registry Mumber 7253-99-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7253-99:
(6*7)+(5*2)+(4*5)+(3*3)+(2*9)+(1*9)=108
108 % 10 = 8
So 7253-99-8 is a valid CAS Registry Number.

7253-99-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-bis(2-cyanoethyl)urea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7253-99-8 SDS

7253-99-8Relevant academic research and scientific papers

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