72568-49-1

Upstream product

• 2698-41-1 o-chlorobenzylidene malononitrile 
• 141-97-9 ethyl acetoacetate 
• 89-98-5 2-chloro-benzaldehyde 
• 109-77-3 malononitrile 

Downstream Products

• 119337-23-4 ethyl 4,7-bis(2-chlorophenyl)-8,8-dicyano-2-methyl-5-oxo-1,6-diazanaphthalene-3-carboxylate 
• 119337-18-7 ethyl 7-amino-4-(2-chlorophenyl)-8-cyano-5,6-dihydro-2-methyl-5-oxo-1,6-diazanaphthalene-3-carboxylate 
• 89607-38-5 6-amino-(2-chlorophenyl)-1,4-dihydro-3-methylpyrano<2,3-c>pyrazole-5-carbonitrile 
• 34158-76-4 2-chlorobenzaldehyde phenylhydrazone 
• 1605301-90-3 ethyl 6-acetamido-5-carbamoyl-4-(2-chlorophenyl)-2-methyl-4H-pyran-3-carboxylate 
• 119337-28-9 ethyl 5-amino-4-(2-chlorophenyl)-6-cyano-7,8-dihydro-2-methyl-7-oxo-1,8-diazanaphthalene-3-carboxylate 
• 119337-31-4 ethyl 5-(2-chlorophenyl)-3,4-dihydro-2,7-dimethyl-4-oxo-5H-pyrano<2,3-d>pyrimidine-6-carboxylate 

Relevant academic research and scientific papers

Mesoporous KIT-6 supported ionic liquids as new and highly effective heterogeneous catalysts for three-component synthesis of 2-amino-3-cyano-4H-pyrans

A series of mesoporous KIT-6 supported ionic liquids were prepared and tested as effective and practical catalysts for the synthesis of 2-amino-3-cyano-4H-pyrans. The effects of type of catalysts, catalyst amount, and catalyst stability have also been inv

Ferric Sulfasalazine Sulfa Drug Complex Supported on Cobalt Ferrite Cellulose; Evaluation of Its Activity in MCRs

Abstract: The green and nano catalyst was simply prepared through the reaction of ferric sulfasalazine with nanomaterial CoFe2O4-cellulose as a magnetic biopolymer surface. This novel heterogeneous organometallic catalyst was charact

Novel biocompatible core/shell Fe3O4?NFC?Co(ii) as a new catalyst in a multicomponent reaction: An efficient and sustainable methodology and novel reusable material for one-pot synthesis of 4: H -pyran and pyranopyrazole in aqueous media

Today, due to the developing need for inexpensive catalysts, recyclable magnetic nanocatalysts immobilized on polysaccharides possess many advantages over classical heterogeneous catalysts. However, cellulose has been an appealing material in catalysis sc

Preparation and characterization of Ca-modified Co/Al2O3 and its catalytic application in the one-pot synthesis of 4H-pyrans

Abstract: In this research, Co/Ca–Al2O3 composite as a heterogeneous nanocatalyst was synthesized by the co-precipitation method. The effect of Ca addition on the textural properties and the catalytic activity was investigated. The r

Synthesis of novel multi-OH functionalized ionic liquid and its application as dual catalyst-solvent for the one-pot synthesis 4H-pyrans

In the present work, triethanolammonium 3-hydroxypropane-1-sulfonate [TEA][HPS] as a novel multi-OH functionalized ionic liquid was synthesized. [TEA][HPS] was characterized by 1HNMR, 13CNMR, FT-IR and elemental analysis. In addition

Synthesis, biological evaluation and molecular docking study of 1,2,3-1H-triazoles having 4H-pyrano[2,3-d]pyrimidine as potential Mycobacterium tuberculosis protein tyrosine phosphatase B inhibitors

Some heterocycles, namely 2-amino-4H-pyran-3-carbonitriles, were synthesized in a three-component reaction from substituted benzaldehydes, malononitrile, and ethyl acetoacetate. These heterocycles have been converted subsequently into 4H-pyrano[2,3-d]pyri

DABCO catalyzed green and efficient synthesis of 2-Amino-4H-Pyrans and their biological evaluation as antimicrobial and anticancer agents

Aim and Objective: The present method is simple, green and highly efficient for the synthesis of 2-amino-4H-pyran derivatives which are achieved by a one pot three component cyclocondensation of aldehyde, malanonitrile and ethyl acetoacetate or methyl acetoacetate using DABCO under solvent free with grinding conditions at room temperature. Material and Methods: Some of the synthesized compounds were screened for their antimicrobial and antifungal activity. The study shows that these compounds show good antimicrobial activity. Furthermore, eight of the synthesized compounds were selected for screening of their anticancer activity against human astrocytoma-glioblastoma cell line (U373MG). Some of the compounds show good anticancer activity. Result: Grinding synthesis of 2-amino-4H-pyran derivatives catalyzed by DABCO with various aromatic aldehydes under solvent-free conditions at room temperature was examined. The obtained compounds (22 entries) were well synthesized in good to excellent yields. Conclusion: The present method is simple, rapid, and most efficient green protocol for the synthesis of 2-amino-4H-pyran derivatives using highly inexpensive and easily available DABCO as an efficient catalyst under grinding and solvent free condition at room temperature.

Synthesis of Fe3 O4 nanoparticles bound with polyethylene glycol substituted 1-methyl imidazolium bromide and their application as nanomag-netic and recyclable phase-transfer catalysts for the green and efficient synthesis of 4H-pyra

Immobilization of polyethylene glycol substituted 1-methylimidazolium bromide on the surface of Fe3 O4 magnetic nanoparticles led to the synthesis of powerful and recyclable heterogeneous phase-transfer catalysts which were successfu

One-pot synthesis of some 2-amino-4H-chromene derivatives using triethanolamine as a novel reusable organocatalyst under solvent-free conditions and its application in electrosynthesis of silver nanoparticles

A wide variety of 2-amino-4H-chromene derivatives with diverse substituents on the 4H-chromene ring were efficiently prepared via one-pot three-component reaction of an aromatic aldehyde and malononitrile with 2-hydroxynaphthalene-1,4-dione, ethyl acetoac

Bis(4-pyridylamino)triazine-stabilized magnetite nanoparticles: preparation, characterization and application as a retrievable catalyst for the green synthesis of 4H-pyran, 4H-thiopyran and 1,4-dihydropyridine derivatives

Synthesis of bis(4-pyridylamino)triazine stabilized on silica-coated nano-Fe3O4 particles, and their feasibility as a reusable heterogeneous basic catalyst are reported. The catalytic performance of this novel material was studied fo