725705-48-6Relevant academic research and scientific papers
Preparation of 2-aminopyridoimidazoles and 2-aminobenzimidazoles via phosphorus oxychloride-mediated cyclization of aminoureas
Deasy, Rebecca E.,Slattery, Catherine N.,Maguire, Anita R.,Kjell, Douglas P.,Hawk, Mai Khanh N.,Joo, Jung Min,Gu, Rui Lin,Moynihan, Humphrey
, p. 3688 - 3695 (2014/05/06)
The novel preparation of 2-aminopyridoimidazoles and 2-aminobenzimidazoles via the cyclization of (2-aminopyridin-3-yl)urea and (2-aminophenyl)urea substrates in the presence of phosphorus oxychloride is described. This methodology is demonstrated for a range of urea substrates with aminoimidazole products obtained in good yields and with excellent levels of purity.
Specific features of nucleophilic substitution in 1-chloro-3,4- dinitrobenzene
Zotova,Kushakova,Kuznetsov,Rodin,Garabadzhiu
, p. 1473 - 1476 (2007/10/03)
Effects of the solvent, temperature, and nucleophile nature on the selectivity of nucleophilic substitution in 1-chloro-3,4-dinitrobenzene were studied, and optimal conditions were found for the synthesis and isolation of particular products.
