725712-44-7

Basic information

• Product Name: 1-(3-chloro-6-methyl-benzo[b]thiophene-2-carbonyl)-3-p-tolyl-thiourea
• CAS NO: 725712-44-7
• Molecular Weight: 374.915
• Mol File: 725712-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-chloro-6-methyl-benzo[b]thiophene-2-carbonyl)-3-p-tolyl-thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-chloro-6-methyl-benzo[b]thiophene-2-carbonyl)-3-p-tolyl-thiourea(725712-44-7)
• EPA Substance Registry System: 1-(3-chloro-6-methyl-benzo[b]thiophene-2-carbonyl)-3-p-tolyl-thiourea(725712-44-7)

Safety Data

• Hazardous Substances Data: 725712-44-7(Hazardous Substances Data)

Upstream product

• 7141-87-9 α-Brom-p-methyl-hydrozimtsaeure 
• 106-49-0 p-toluidine 
• 34576-87-9 3-Chlor-6-methyl-benzo--thiophen-2-carbonsaeurechlorid 

Relevant articles and documents

Synthesis of heterocycles from the products of anionic arylation of unsaturated compounds. 7*. Products of haloarylation of acrylic acid and its esters in the synthesis of benzo[b]thiophene derivatives

3-Chloro-2-chlorocarbonylbenzo[b]thiophenes were obtained on oxidation of Meerwein reaction products, viz. 3-aryl-2-halopropionic acids and their esters, with thionyl chloride in the presence of N-benzyl-N-methylmorpholinium chloride. Disubstituted thioureas were synthesized by the reaction of these compounds with ammonium thiocyanate and aromatic amines, and were cyclized by interaction with iodoacetic acid with the formation of 4-thiazolidinone derivatives. The same cyclization in the presence of aromatic aldehydes leads to the formation of the corresponding 5-arylidene-substituted 4-thiazolidinones.