725718-33-2

Upstream product

• 725718-34-3 2,2-Dimethyl-propionic acid (2R,3R,4R,5R,6S)-5-acetylamino-6-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-4-(imidazole-1-carbothioyloxy)-tetrahydro-pyran-3-yl ester 
• 725718-32-1 2,2-Dimethyl-propionic acid (2R,3R,4R,5R,6S)-5-acetylamino-6-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-4-phenoxythiocarbonyloxy-tetrahydro-pyran-3-yl ester 
• 592533-32-9 benzyl 2-acetamido-2-deoxy-4,6-di-O-pivaloyl-α-D-galactopyranoside 

Downstream Products

• 725718-42-3 2,2-Dimethyl-propionic acid (2R,3R,5R,6R)-5-acetylamino-6-(bis-benzyloxy-phosphoryloxy)-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

Synthesis of UDP-GalNAc analogues as probes for the study of polypeptide-α-GalNAc-transferases. Part 2

The synthesis of four UDP-GalNAc analogues (1-4) is described. The 3-, 4- and 6-deoxygenated analogues 1-3 were obtained by way of a divergent strategy starting from a 3,6-di-O-pivaloyl GlcNAc derivative as a common precursor. Analogue 4 bearing a N-trifluoroacetamido group was prepared from the trifluoromethylated oxazoline 24 as key intermediate. These compounds were designed to probe the substrate specificity of polypeptide-α-GalNAc transferases.