72597-68-3Relevant academic research and scientific papers
Thia-aza compounds with a β-lactam ring
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, (2008/06/13)
2-Penem-3-carboxylic acid compounds of the formula STR1 in which R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom or an etherified mercapto group and R2 represents hydroxy or a radical R2A forming together with the carbonyl grouping --C(=O)-- a protected carboxyl group, 1-oxides thereof, as well as salts of such compounds having salt-forming groups, in racemic and optically active form, processes for their preparation, pharmaceutical compositions containing such compounds, and their use as antibiotics, and intermediates and their processes which are useful in the production of the compounds of the formula I.
Antibacterial agents, and 4-thio azetidinone intermediates
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, (2008/06/13)
This invention relates to 2-substituted and 2,6-disubstituted penem compounds of the formula STR1 wherein Y is hydrogen, halo or certain organic substituents and X represents certain organic substituents. Also included in the invention are pharmaceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3-position is protected as by an easily removable ester protecting group. The compounds of the present invention are potent antibacterial agents or are of use as intermediates in the preparation of such agents.
2-Methylpenem-3-carboxylic acid antibiotics
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, (2008/06/13)
There is described the preparation of novel 2-penem-3-carboxylic acid compounds having the formula STR1 and easily cleavable esters and carboxylic acid salts thereof. The compounds of formula I, particularly the dextrorotatory isomers thereof, are potent
