72604-99-0

Upstream product

• 506-59-2 N,N-dimethylammonium chloride 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 30354-18-8 N,N-dimethyl(methylene)ammonium chloride 
• 50-00-0 formaldehyd 

Downstream Products

• 81471-51-4 2-Amino-5,6-dihydro-8-methoxy-benzochinol-3-yl-phenylketon 
• 33279-02-6 6-methoxy-2-piperidinomethyl-3,4-dihydro-2H-naphthalen-1-one; hydrochloride 

Relevant academic research and scientific papers

Facile synthesis of polycyclic pyridines, bipyridines, and oligopyridines

The preparation of polycyclic heterocycles with one or more nitrogen atoms and different binding angles by a domino reaction is described, These compounds (4-6, 8a-b) are formed by the reaction of β-amino ketone hydrochlorides 1 or 2 (Mannich bases) with ketones 3. Especially the synthesis of the terpyridines 8a and 8b in a double domino reaction is very useful (yield 70 and 59%) and opens a route to torands. VCH Verlagsgesellschaft mbH, 1996.

Studies on the Amine Exchange Reactions in C-Mannich Bases

Amine exchange reactions are extended to C-Mannich bases derived from 6-methoxy-1-tetralone and the reaction intermediate during exchange reaction was isolated and characterised.