72653-66-8

Basic information

• Product Name: 2-methyl-2-<1-(phenylthio)butyl>-1-cyclohexanone
• Synonyms: 2-methyl-2-<1-(phenylthio)butyl>-1-cyclohexanone
• CAS NO: 72653-66-8
• Molecular Weight: 276.443
• Mol File: 72653-66-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methyl-2-<1-(phenylthio)butyl>-1-cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2-<1-(phenylthio)butyl>-1-cyclohexanone(72653-66-8)
• EPA Substance Registry System: 2-methyl-2-<1-(phenylthio)butyl>-1-cyclohexanone(72653-66-8)

Safety Data

• Hazardous Substances Data: 72653-66-8(Hazardous Substances Data)

Upstream product

• 1126-80-3 (n-butylthio)benzene 
• 72653-47-5 α-chlorobutyl phenyl sulfide 
• 19980-35-9 1-trimethylsilyloxy-2-methyl-1-cyclohexene 

Downstream Products

• 1197-78-0 2-butyl-2-methyl-cyclohexanone 

Relevant articles and documents

Thioalkylation of Enolates, II. α-Thioalkylation of Zinc Enolates to α,α-Disubstituted Ketones

An α-alkylation of the 2-methylcycloalkanones 1 and 4 at the higher substituted carbon can be achieved by thioalkylation of the corresponding zinc enolates with the α-chlorosulfides 3.The desulfurization can be carried out with either Raney nickel or lithium in diethylamine for compounds which contain double or triple bonds. Key Words: Zinc enolates, thioalkylation of / Ketones, α,α-disubstituted / Desulfurization

α-Alkylation and α-alkylidenation of carbonyl compounds: Lewis acid-promoted phenylthioalkylation of o-silylated enolates

The O-silylated enolates of ketones, aldehydes, esters, and lactones can be phenylthioalkylated in the presence of Lewis acids; reductive or oxidative sulphur-removal gives the regiospecifically α-alkylated or alkylidenated carbonyl compounds.