7267-97-2

Basic information

• Product Name: (16S)-Curan-17-oic acid methyl ester
• Synonyms: (16S)-Curan-17-oic acid methyl ester
• CAS NO: 7267-97-2
• Molecular Formula: C₂₀H₂₆N₂O₂
• Molecular Weight: 326.43264
• Mol File: 7267-97-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (16S)-Curan-17-oic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (16S)-Curan-17-oic acid methyl ester(7267-97-2)
• EPA Substance Registry System: (16S)-Curan-17-oic acid methyl ester(7267-97-2)

Safety Data

• Hazardous Substances Data: 7267-97-2(Hazardous Substances Data)

Upstream product

• 2912-08-5 (-)-19,20-dihydroakuammicine 
• 639-43-0 (-)-akuammicine 
• 1322613-98-8 C₁₆H₁₈N₂O₂ 

Downstream Products

• 1233498-33-3 (-)-leucoridine C 
• 18397-07-4 (+)-geissoschizoline 

Relevant articles and documents

Biomimetic total syntheses of (-)-leucoridines A and C through the dimerization of (-)-dihydrovalparicine

Concise biomimetic syntheses of the Strychnos-Strychnos-type bis-indole alkaloids (-)-leucoridine A (1) and C (2) were accomplished through the biomimetic dimerization of (-)-dihydrovalparicine (3). En route to 3, the known alkaloids (+)-geissoschizoline (8) and (-)-dehydrogeissoschizoline (10) were also prepared. DFT calculations were employed to elucidate the mechanism, which favors a stepwise aza-Michael/spirocyclization sequence over the alternate hetero-Diels-Alder cycloaddition reaction. Concise biomimetic syntheses of the Strychnos-Strychnos-type bis-indole alkaloids (-)-leucoridine A and C were accomplished through the biomimetic dimerization of (-)-dihydrovalparicine. DFT calculations were used to elucidate the mechanism, which favors a stepwise aza-Michael/spirocyclization sequence over the alternate hetero-Diels-Alder cycloaddition reaction.