72676-96-1 Usage
General Description
4-oxo-1,4-dihydro-3-pyridinecarboxylic acid, also known as alpha-ketohistidine, is a chemical compound with the molecular formula C6H5NO3. It is a derivative of histidine, an essential amino acid involved in various physiological processes in the human body. 4-oxo-1,4-dihydro-3-pyridinecarboxylic acid is formed through the oxidation of histidine and is a key intermediate in the biosynthesis of other important molecules such as carnosine, anserine, and other dipeptides. It has been studied for its potential role in oxidative stress and its antioxidant properties, making it of interest in the fields of biochemistry and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 72676-96-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,7 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 72676-96:
(7*7)+(6*2)+(5*6)+(4*7)+(3*6)+(2*9)+(1*6)=161
161 % 10 = 1
So 72676-96-1 is a valid CAS Registry Number.
72676-96-1Relevant articles and documents
The Reaction of N -Trimethylsilyl-Substituted Heteroarylamines with Esters and Thioesters: An Efficient Protocol to Access Diheteroarylamides
Koperniku, Ana,Zamiri, Maryam,Grierson, David S.
, p. 1779 - 1790 (2019/04/05)
The S -benzyl thioester and methyl ester derivatives of a representative 4-pyridinone-based carboxylic acid were sufficiently activated to react efficiently in amide coupling reactions with the amide anion generated in situ from the N -trimethylsilyl derivative of different weakly nucleophilic heteroarylamines. In acetonitrile as solvent, the precipitated diheteroarylamide products were isolated in pure form by vacuum filtration. This simple amide bond forming protocol can be readily adapted to the parallel synthesis of compound libraries.
