72680-07-0

Usage

Class

Thienodiazepine

Psychoactive Drug

Yes

Uses

Sedative, anxiolytic, and hypnotic agent

Treatment of

Anxiety, insomnia, and panic disorders

Mechanism of Action

Enhances the effect of gamma-aminobutyric acid (GABA) in the brain

Potency

Highly potent

Onset of Action

Fast

Duration of Effect

Short

Potential Issues

Abuse, dependence, and withdrawal symptoms

Controlled Substance

Yes, in many countries

Forms Available

Tablets or powder for oral administration

Upstream product

• 72693-60-8 5-anilino-1H-v-triazole-4-carboxylic acid 

Relevant academic research and scientific papers

Studies on v-Triazoles. Part I: Synthesis of 4,9-Dihydro-9-oxo-1H-v-triazolo quinolines by cyclization of 5-arylamino-v-triazole-4-carboxylic acids with polyphosphoric acid.

The cyclization of 5-arylamino-v-triazole-4-carboxylic acids with polyphosphoric acid leads to high yields of the corresponding 4,9-dihydro-9-oxo-v-triazolo quinolines which are potent antiallergic agents.

Triazolo [4,5-b] quinolines and prophylaxis of allergic diseases with them

The invention provides novel compounds of formula (I). STR1 and pharmaceutically acceptable salts thereof wherein R1, R2, R3 and R4 which may be the same or different, represent hydrogen, halogen, lower alkyl, and lower alkoxy, or any adjacent two of R1 to R4 taken together represent an alkylene group containing from 3 to 5 carbon atoms or a 1,4-buta-1,3-dienylene group. The compounds are useful as anti-allergic agents.