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N-(2-methylbenzylidene)benzenesulfonamide is a chemical compound with the molecular formula C14H13NO2S. It is an organic compound that belongs to the class of sulfonamides, which are derivatives of benzene with a sulfonamide group attached. This specific compound features a 2-methylbenzylidene group, which is a benzylidene group with a methyl group attached to the benzene ring. The compound is known for its potential applications in various chemical and pharmaceutical processes, such as the synthesis of dyes and pharmaceutical intermediates. It is also recognized for its role in the development of certain types of drugs, particularly those with anti-inflammatory properties. The compound's structure and properties make it a subject of interest in organic chemistry and medicinal chemistry research.

727-38-8

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727-38-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 727-38-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,2 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 727-38:
(5*7)+(4*2)+(3*7)+(2*3)+(1*8)=78
78 % 10 = 8
So 727-38-8 is a valid CAS Registry Number.

727-38-8Relevant academic research and scientific papers

Visible-light, iodine-promoted formation of n-sulfonyl imines and n-alkylsulfonamides from aldehydes and hypervalent iodine reagents

Hopkins, Megan D,Brandeburg, Zachary C.,Hanson, Andrew J.,Lamar, Angus A

, (2018/08/04)

Alternative synthetic methodology for the direct installation of sulfonamide functionality is a highly desirable goal within the domain of drug discovery and development. The formation of synthetically valuable N-sulfonyl imines from a range of aldehydes,

Nitroxyl-Radical-Catalyzed Oxidative Coupling of Amides with Silylated Nucleophiles through N-Halogenation

Moriyama, Katsuhiko,Kuramochi, Masako,Fujii, Kozo,Morita, Tsuyoshi,Togo, Hideo

supporting information, p. 14546 - 14551 (2016/11/23)

A nitroxyl-radical-catalyzed oxidative coupling reaction between amines with an N-protecting electron-withdrawing group (EWG) and silylated nucleophiles was developed to furnish coupling products in high yields, thus opening up new frontiers in organocatalyzed reactions. This reaction proceeded through the activation of N-halogenated amides by a nitroxyl-radical catalyst, followed by carbon–carbon coupling with silylated nucleophiles. Studies of the reaction mechanism indicated that the nitroxyl radical activates N-halogenated amides, which are generated from N-EWG-protected amides and a halogenation reagent, to give the corresponding imines.

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