727-49-1

Basic information

• Product Name: HEPTAFLUORO-2-NAPHTHOL
• Synonyms: HEPTAFLUORO-2-NAPHTHOL;BETA-HYDROXY-HEPTAFLUORONAPHTHALENE;Heptafluoro-2-naphthol 97%;Heptafluoro-2-naphthol97%;beta-Hydroxy-heptafluoronaphthalene,97%;1,3,4,5,6,7,8-Heptafluoro-2-naphthol;Perfluoro-2-naphthol;1,3,4,5,6,7,8-Heptafluoronaphthalen-2-ol
• CAS NO: 727-49-1
• Molecular Formula: C₁₀HF₇O
• Molecular Weight: 270.1
• Mol File: 727-49-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 120-124 °C
• Boiling Point: 275℃
• Flash Point: 120℃
• Appearance: /
• Density: 1.783
• Vapor Pressure: 0.00304mmHg at 25°C
• Refractive Index: 1.518
• PKA: 3.94±0.50(Predicted)
• CAS DataBase Reference: HEPTAFLUORO-2-NAPHTHOL(CAS DataBase Reference)
• NIST Chemistry Reference: HEPTAFLUORO-2-NAPHTHOL(727-49-1)
• EPA Substance Registry System: HEPTAFLUORO-2-NAPHTHOL(727-49-1)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• Hazardous Substances Data: 727-49-1(Hazardous Substances Data)

Usage

Chemical Properties

grey powder

Uses

Heptafluoronaphthalen-2-ol is a building block and an intermediate in the synthesis and characterization of other amino fluoro derived compounds.

InChI:InChI=1/C10HF7O/c11-3-1-2(4(12)8(16)7(3)15)6(14)10(18)9(17)5(1)13/h18H

Upstream product

• 313-72-4 octafluoronaphthalene 
• 74527-16-5 1,3,4,5,6,7,8-heptafluoro-2-naphthyl prop-2-enyl ether 
• 74527-15-4 1,3,4,5,6,7,8-heptafluoro-1-(prop-2-enyl)-naphthalen-2-one 

Downstream Products

• 1201-31-6 2,3,4,5-tetrafluorobenzoic acid 
• 652-03-9 3,4,5,6-tetrafluorophthalic acid 
• 69472-72-6 2,3,4,5-tetrafluoro-6-(fluoromethyl)phenylglyoxylic acid 
• 3824-73-5 2-Benzoyloxyheptafluornaphthalin 
• 78695-66-6 2-benzyl-4,5,6,7,8,9-hexafluoronaphtho<2,1-b>furan 
• 78695-67-7 2-(2,5-dimethylbenzyl)-4,5,6,7,8,9-hexafluoronaphtho<2,1-b>furan 

Relevant articles and documents

THE PREPARATION AND REACTIONS OF 1,3,4,5,6,7,8-HEPTAFLUORO-2-NAPHTHYL PROP-2-ENYL ETHER: FORMATION OF 1,3,4,5,6,7,8-HEPTAFLUORO-1-(PROP-2-ENYL)NAPHTHALEN-2-ONE AND THE PHOTOLYSIS AND PYROLYSIS OF THIS KETONE

1,3,4,5,6,7,8-Heptafluoro-2-naphthyl prop-2-enyl ether (8) was isomerised in boiling xylene to 1,3,4,5,6,7,8-heptafluoro-1-(prop-2-enyl)naphthalen-2-one (9).Photolysis of (9) gave 2,5,7-trifluoro-3,4-(tetrafluorobenzo)tricyclo2,7>non-3-en-6-one (11) (by a addition) and 1,2,7-trifluoro-3,4-(tetrafluorobenzo)tricyclo2,7>non-3-en-8-one (12) (via an initial photochemically-allowed sigmatropic shift).Pyrolysis of (9) at 455 deg C also gave (11), while at 490 deg C, both (9) and (11) gave 1-fluorovinyl 4,5,6,7,8-pentafluoro-1-naphthyl ketone (19).

REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. II. NUCLEOPHILIC SUBSTITUTION IN NITROHALOGENO AND POLYFLUORINATED AROMATIC COMPOUNDS

The possibility of aromatic nucleophilic substitution in liquid ammonia was investigated for the case of the reaction of p-nitrochlorobenzene, 2,4-dinitrochlorobenzene, hexafluorobenzene, bromopentafluorobenzene, pentafluorobenzene, and octafluoronaphthalene with a series of charged nucleophiles (potassium hydroxide and sulphite, alcoholates, sodium azide, thiophenolate, phenolate, and sulfide) at -70 to -33 deg C.It was shown that alkyl ethers of p-nitrophenol, phenyl p-nitrophenyl sulfide, 2,4-dinitrophenyl azide, polyfluorinaqted phenols, and their ethers can be obtained with good yields.Comparisons of the results with published data on the rate of the same reactions in other solvents shows that liquid ammonia is highly effective as a solvent for aromatic nucleophilic substitution reactions and in some cases makes it possible to avoid side processes.