7270-83-9 Usage
Uses
Used in Research and Diagnostic Applications:
7-Acetoxy-1-methylquinolinium iodide is used as a fluorogenic substrate for cholinesterase in research and diagnostic applications. The conversion of the non-fluorescent compound to a highly fluorescent product allows for the detection and quantification of cholinesterase activity, which is crucial in various biological and medical studies.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 7-Acetoxy-1-methylquinolinium iodide is used as a tool to screen and develop drugs targeting cholinesterase enzymes. By monitoring the enzyme's activity in the presence of potential drug candidates, researchers can assess the effectiveness of these compounds in inhibiting or modulating cholinesterase activity, which is relevant for the treatment of various neurological disorders and conditions.
Used in Environmental Monitoring:
7-Acetoxy-1-methylquinolinium iodide can also be employed in environmental monitoring applications to detect the presence of cholinesterase-inhibiting pollutants or contaminants. By measuring the enzyme's activity in samples taken from the environment, it is possible to identify potential threats to ecosystems and human health caused by these substances.
Check Digit Verification of cas no
The CAS Registry Mumber 7270-83-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,7 and 0 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7270-83:
(6*7)+(5*2)+(4*7)+(3*0)+(2*8)+(1*3)=99
99 % 10 = 9
So 7270-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H12NO2.HI/c1-9(14)15-11-6-5-10-4-3-7-13(2)12(10)8-11;/h3-8H,1-2H3;1H/q+1;/p-1
7270-83-9Relevant academic research and scientific papers
Menger, Fredric M.,Nelson, Kingsley H.,Guo, Yingbo
, p. 2001 - 2002 (1998)
Acetylcholinesterase and chymotrypsin are able to catalyze hydrolyses of vesicle-bound substrates at rates that depend upon the ability of the substrates to project beyond the membrane surface.
Caturla, Francisco,Enjo, Juan,Bernabeu, M. Carmen,Le Serre, Stephanie
, p. 1903 - 1911 (2004)
Combinatorial development of new catalysts with phosphodiesterase and esterase activities requires specific fluorescent probes for rapid visual detection of hydrolytic activity. Such fluorescent probes have been synthesized with special attention to solubility in water and stability towards spontaneous hydrolysis at a given pH. The probes reported here include compound 5 based on a fluorescein fluorophore, compound 12 for FRET-detection of phosphodiester hydrolysis and compound 25 based on a quinolinium fluorophore.
