72700-07-3Relevant academic research and scientific papers
Differential Effects of Structural Modifications on the Competition of Chalcones for the PIB Amyloid Imaging Ligand-Binding Site in Alzheimer's Disease Brain and Synthetic Aβ Fibrils
Fosso, Marina Y.,McCarty, Katie,Head, Elizabeth,Garneau-Tsodikova, Sylvie,LeVine, Harry
, p. 171 - 176 (2016)
Alzheimer's disease (AD) is a complex brain disorder that still remains ill defined. In order to understand the significance of binding of different clinical in vivo imaging ligands to the polymorphic pathological features of AD brain, the molecular chara
New chalcone-3-O-glycoside derivatives: Synthesis and characterization
?elik, Gonca
, p. 598 - 601 (2020/04/27)
Seven novel carbohydrate conjugates of new chalcone-3-O-glycosides were synthesized and characterized. Starting from the substituted 3′-hydroxyarylmethylacetophenone derivatives (chalcones) with α-acetobromoglucose in anhydrous acetone were synthesized 2,
Mesomorphic study of novel chalconyl-ester-based nonisomeric series: Synthesis and characterization
Sharma, Vinay S.,Patel
, p. 13 - 27 (2017/03/08)
A newly designed homologues series: 3-(3-(4-(Dimethylamino) phenyl) acrylonyl) phenyl 3-(4-n-alkoxyphenyl) acrylate has been synthesized and studied through chalconyl ester linking group at (meta) position. The series consists of 13 compounds, in which C1 to C4 homologue are nonliquid crystal, while C5 to C18 exhibit nematic phase, and C12 to C18 shows smectic and nematic phase with enantiotropically manner. Mesophase image of present compounds are rod like, needle and threaded type textures investigated by POM. All this compounds were characterized by elemental analysis, FT-IR and 1H NMR. The mesomorphism is measured by POM, DSC, and molecular packing is determined by XRD technique. The following synthesized chalconyl ester-based compounds C5 to C12 shows antibacterial as well as antifungal activity compared with corresponding standard drugs. Analytical and spectral data confirmed the molecular structures of homologous series.
Synthesis, characterization and biological evaluation of some new isoxazoline derivatives
Jain, Dinesh K.,Goyal, Neeraj,Bhadoriya, Upendra
, p. 789 - 792 (2013/05/22)
Isoxazoline represents a unique class of nitrogen- and oxygen-containing five-membered heterocycles, a class of compounds of great importance in biological chemistry. Isoxazoline is considered as one of the most potent antimicrobial compound. Isoxazoline
