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Z-VAL-GLY-GLY-OBZL is a chemical compound that serves as a substrate for thrombin, a serine protease enzyme crucial in the blood clotting process. It is composed of the amino acid sequence valine-glycine-glycine, with a benzyloxycarbonyl (OBZL) group attached to the terminal glycine residue. Z-VAL-GLY-GLY-OBZL is instrumental in research and drug development, focusing on the study of thrombin activity and the design of selective inhibitors targeting this enzyme. The insights gained from understanding its interactions and mechanisms of action can contribute to the development of therapeutic interventions for conditions associated with excessive blood clotting, such as heart attacks and strokes.

72722-19-1

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72722-19-1 Usage

Uses

Used in Pharmaceutical Research and Development:
Z-VAL-GLY-GLY-OBZL is used as a research tool for studying the activity of thrombin, a serine protease enzyme involved in blood clotting. It aids in understanding the enzyme's mechanisms of action and interactions with other molecules, which is essential for developing drugs that can selectively target thrombin.
Used in Drug Design:
Z-VAL-GLY-GLY-OBZL is utilized as a template in the design of inhibitors that can selectively target thrombin. This selective targeting is crucial for developing drugs that can effectively treat conditions related to excessive blood clotting without causing unwanted side effects.
Used in Therapeutic Interventions for Blood Clotting Disorders:
Z-VAL-GLY-GLY-OBZL is used as a basis for developing therapeutic interventions for conditions such as heart attacks and strokes, which are related to excessive blood clotting. By understanding the interactions of Z-VAL-GLY-GLY-OBZL with thrombin, researchers can design drugs that can modulate the enzyme's activity, potentially preventing or treating these life-threatening conditions.
Used in Diagnostics:
Z-VAL-GLY-GLY-OBZL can be employed as a diagnostic tool to assess the activity of thrombin in patients, helping to identify those at risk of blood clotting disorders and monitor the effectiveness of treatments.
Used in Biochemical Education:
Z-VAL-GLY-GLY-OBZL can serve as an educational tool in biochemical courses, illustrating the principles of enzyme-substrate interactions, the role of protease enzymes in physiological processes, and the importance of selective drug targeting in medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 72722-19-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,7,2 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 72722-19:
(7*7)+(6*2)+(5*7)+(4*2)+(3*2)+(2*1)+(1*9)=121
121 % 10 = 1
So 72722-19-1 is a valid CAS Registry Number.
InChI:InChI=1/C24H29N3O6/c1-17(2)22(27-24(31)33-16-19-11-7-4-8-12-19)23(30)26-13-20(28)25-14-21(29)32-15-18-9-5-3-6-10-18/h3-12,17,22H,13-16H2,1-2H3,(H,25,28)(H,26,30)(H,27,31)

72722-19-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Z-VAL-GLY-GLY-OBZL

1.2 Other means of identification

Product number -
Other names Z-L-VALYL-L-GLYCYL GLYCINE BENZYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72722-19-1 SDS

72722-19-1Upstream product

72722-19-1Downstream Products

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