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Upstream product

• 934-32-7 1H-benzimidazol-2-amine 
• 141-97-9 ethyl acetoacetate 
• 587-04-2 m-Chlorobenzaldehyde 

Relevant academic research and scientific papers

Preparation and characterization of copper/polysulfonamide complex immobilized on geraphene oxide as a novel catalyst for the synthesis of pyrimido[1,2-a]benzimidazoles

Copper–polysulfonamide complex immobilized on geraphene oxide as a novel heterogeneous catalyst (GO@PSA-Cu) was synthesized and the structure and morphology of catalyst were characterized with various analytical techniques such as Fourier-transform infrar

Ionic liquid-catalyzed synthesis of triazoloquinazolinones, chromeno[4,3-d]benzothiazolopyrimidines and benzoimidazopyrimidine derivatives

1,3-Disulfonic acid imidazolium trifluoroacetate ([Dsim][CF3CO2]) was employed as an efficient, homogeneous and recyclable ionic liquid catalyst for the synthesis of triazoloquinazolinones, chromeno[4,3-d]benzothiazolopyrimidines and

Preparation method of medical intermediate dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine derivative

The invention discloses a preparation method of a medical intermediate, namely a dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine derivative, belonging to the technical field of biological medicines. The method comprises the following steps: taking aromatic alde

Synthesis of benzo[4,5]imidazo[1,2-: A] pyrimidines and 2,3-dihydroquinazolin-4(1 H)-ones under metal-free and solvent-free conditions for minimizing waste generation

Br?nsted acidic ionic liquid was found to be an efficient and recyclable catalyst for the synthesis of benzo[4,5]imidazo[1,2-a]pyrimidines and 2,3-dihydroquinazolin-4(1H)-ones. The reactions proceeded smoothly with a broad scope of substrates providing the expected products in good to excellent yields under an atom-economical pathway. The low-cost recyclable catalyst, metal- and solvent-free conditions, and the ease of product isolation are the highlighted advantages in solving the issue of trace metal contamination in synthesized pharmaceuticals.

An efficient and practical synthesis of benzazolo[2,1-b]quinazolinones and triazolo[2,1-b]quinazolinones catalyzed by nano-sized NS-C4(DABCO-SO3H)2)·4Cl

In this study, 4,4′-(butane-1,4-diyl)bis(1-sulfo-1,4-diazabicyclo[2.2.2]octane-1,4-diium)tetrachloride (NS-C4(DABCO-SO3H)2)·4Cl is used as a nano-sized Br?nsted acid catalyst for the efficient and preferment synthesis of b

Poly(vinylpyrrolidonium) perchlorate catalyzed one-pot synthesis of tricyclic dihydropyrimidine derivatives

A simple and efficient procedure for the synthesis of benzo[4,5]imidazo[1,2-α]pyrimidine and 2-amino-4-substituted-1,4-dihydrobenzo[4,5]imidazolo[1,2-α]pyrimidine-3-carbonitrile derivatives using poly(vinylpyrrolidonium) perchlorate {[PVPH]ClO4

One-pot synthesis of pyrimido[1,2-a]benzimidazoles under solvent-free conditions

A series of pyrimido[1,2-a]benzimidazoles were obtained from aldehydes, 2-aminobenzimidazole and ethyl acetoacetate in good-to-excellent yields by a simple, mild, and efficient procedure utilizing N,N,N′,N′- tetrabromobenzene-1,3-disulfonamide (TBBDA) and

Thiamine hydrochloride (VB1): An efficient promoter for the one-pot synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine and [1,2,4]triazolo[1,5- a]pyrimidine derivatives in water medium

A straightforward and general method has been developed for the synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine and [1,2,4]triazolo[1,5-a]pyrimidine derivatives by simply combining 2-aminobenzimidazole or 3-amino-1,2,4-triazole, aldehyde, and β-dicarbonyl